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StarD5 Knock-out Mouse

Info

Catalogue Number 154034
Antigen/Gene or Protein Targets StarD5
Disease Keywords Heart disease, heart attack and stroke
Model Knock-Out
Relevance StarD5 protein is knocked out in the entire mouse to study the effects of disrupting pathways associated with cholesterol and resultant pathological conditions.
Production Details The StarD5 knock-out mouse was produced by designing a guide RNA to create a double-strand cleavage upstream of the ATG start site. Pups were obtained, screened and sequenced. Heterozygous male and female mice were crossed to generate homozygous StarD5 knock-out mice.
Research Area Cardiovascular, Drug Discovery & Development

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