Anti-human IGF-1 receptor (IGF-1R) [24-58] monoclonal antibody
Invented at University of Cambridge
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 154020 |
| Applications | N/A |
| Antigen/Gene or Protein Targets | Human Insulin-like Growth Factor-1 receptor |
| Synonyms | IGF-1 R |
| Reactivity | Human |
| Relevance | Human insulin-like growth factor 1 (IGF-1) receptor is transmembrane tyrosine kinase receptor for insulin-like growth factor 1 hormone. Also activated by IGF-2. IGF receptor plays a crucial role in growth and anabolic metabolism in adults. |
| Host | Mouse |
| Immunogen | Murine fibroblasts over-expressing cloned human IGF-1 receptor |
| Subclass | IgG2a |
| Molecular Weight (kDa) | 135 |
| Myeloma Used | NS1/0 |
| Recommended Growing Conditions | Dulbecco's MEM + 20% FBS |
| Notes | Not tested for any specific application. May work in IP, ELISA, FACS, IF, RIA. Inhibits ligand binding. |
| Research Area | Cell Signaling & Signal Transduction, Metabolism |
References: 2 entries
Soos et al. 1992. J Biol Chem. 267(18):12955-63. PMID: 1377676.
A panel of monoclonal antibodies for the type I insulin-like growth factor receptor. Epitope mapping, effects on ligand binding, and biological activity.
Europe PMC ID: 1377676
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References: 2 entries
Soos et al. 1992. J Biol Chem. 267(18):12955-63. PMID: 1377676.
A panel of monoclonal antibodies for the type I insulin-like growth factor receptor. Epitope mapping, effects on ligand binding, and biological activity.
Add a reference
