Anti-human insulin receptor (IR) [CT-21] monoclonal antibody
Invented at University of Cambridge
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Info
| Catalogue Number | 154017 |
| Applications | N/A |
| Antigen/Gene or Protein Targets | Human Insulin receptor |
| Synonyms | IR, hIR, INSR |
| Reactivity | Human |
| Relevance | Human Insulin Receptor (IR) is a transmembrane tyrosine kinase receptor for insulin. It plays a role in glucose homeostasis by controlling the glucose transport to cells. Malfunction of IR include clinical manifestations such as cancer and diabetes. |
| Host | Mouse |
| Immunogen | GST-fusion protein incorporating intracellular domain of human Insulin receptor |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 135 |
| Recommended Growing Conditions | Dulbecco's MEM + 20% FBS |
| Notes | Not tested for any specific application. May work in IP, ELISA, FACS, IF, RIA. |
| Research Area | Cell Signaling & Signal Transduction, Metabolism |
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