Anti-human insulin receptor (IR) [83-22] monoclonal antibody
Invented at University of Cambridge
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 154011 |
| Applications | N/A |
| Antigen/Gene or Protein Targets | Human Insulin receptor |
| Synonyms | IR, hIR, INSR |
| Reactivity | Human |
| Relevance | Human Insulin Receptor (IR) is a transmembrane tyrosine kinase receptor for insulin. It plays a role in glucose homeostasis by controlling the glucose transport to cells. Malfunction of IR include clinical manifestations such as cancer and diabetes. |
| Host | Mouse |
| Immunogen | Affinity-purified human insulin receptor |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 135 |
| Myeloma Used | NS1/0 |
| Recommended Growing Conditions | Dulbecco's MEM + 20% FBS |
| Notes | Not tested for any specific application. May work in IP, ELISA, FACS, IF, RIA. Inhibits ligand binding. |
| Research Area | Cell Signaling & Signal Transduction, Metabolism |
References: 2 entries
Soos et al. 1986. Biochem J. 235(1):199-208. PMID: 2427071.
Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor.
Europe PMC ID: 2427071
Add a reference
References: 2 entries
Soos et al. 1986. Biochem J. 235(1):199-208. PMID: 2427071.
Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor.
Add a reference
