Anti-RAP [7F1]
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Invented at University Of Maryland
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 153994 |
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Applications
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ELISA IHC WB |
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Antigen/Gene or Protein Targets
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39-kDa receptor-associated protein (RAP) |
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Synonyms
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Receptor Associated Protein antibody |
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Reactivity
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Human |
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Relevance
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LRP1 is an endocytic receptor that interacts with several ligands including alpha 2-macroglobulin. Functionally, the receptor mediates cellular signalling with implications in Alzheimer's disease. This receptor is expressed in brain, liver, and lung and localized to the cytoplasm and nucleus. Expression of LRP1 requires RAP, a molecular chaperone of LRP1. |
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Host
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Mouse |
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Immunogen
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human RAP |
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Subclass
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IgG1 |
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Molecular Weight (kDa)
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39 kDa |
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Research Area
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Epigenetics & Nuclear Signalling, Cell Signaling & Signal Transduction, Neurobiology |
References: 2 entries
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Coukos et al. 1994. Am J Pathol. 144(2):383-92. PMID: 7508685.
Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and the 39-kd receptor-associated protein in human trophoblasts.
Europe PMC ID: 7508685
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References: 2 entries
RECENTLY UPDATED
Coukos et al. 1994. Am J Pathol. 144(2):383-92. PMID: 7508685.
Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and the 39-kd receptor-associated protein in human trophoblasts.
Add a reference
