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Anti-RAP [7F1]

Info

Catalogue Number 153994
Applications ELISA IHC WB
Antigen/Gene or Protein Targets 39-kDa receptor-associated protein (RAP)
Synonyms Receptor Associated Protein antibody
Reactivity Human
Relevance LRP1 is an endocytic receptor that interacts with several ligands including alpha 2-macroglobulin. Functionally, the receptor mediates cellular signalling with implications in Alzheimer's disease. This receptor is expressed in brain, liver, and lung and localized to the cytoplasm and nucleus. Expression of LRP1 requires RAP, a molecular chaperone of LRP1.
Host Mouse
Immunogen human RAP
Subclass IgG1
Molecular Weight (kDa) 39 kDa
Research Area Epigenetics & Nuclear Signalling, Cell Signaling & Signal Transduction, Neurobiology

References

There are 2 reference entries for this reagent.

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References: 2 entries

Coukos et al. 1994. Am J Pathol. 144(2):383-92. PMID: 7508685.

Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and the 39-kd receptor-associated protein in human trophoblasts.

Europe PMC ID: 7508685


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References: 2 entries

Coukos et al. 1994. Am J Pathol. 144(2):383-92. PMID: 7508685.

Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and the 39-kd receptor-associated protein in human trophoblasts.


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