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Anti-LRP1[5A6]

Info

Catalogue Number 153992
Applications IHC IF WB
Antigen/Gene or Protein Targets Low density lipoprotein receptor-related protein-1, light chain
Synonyms LRP1, Low density lipoprotein receptor-related protein 1, apolipoprotein E receptor (APOER), cluster of differentiation 91 (CD91), alpha-2-macroglobulin receptor (A2MR)
Reactivity Mouse, Rat and Human
Relevance LRP1 is an endocytic receptor that interacts with several ligands including alpha 2-macroglobulin. Functionally, the receptor mediates cellular signalling with implications in Alzheimer's disease. This receptor is expressed in brain, liver, and lung and localized to the cytoplasm and nucleus.
Host Mouse
Immunogen recombinant human fragment; 85 kDa LRP
Subclass IgG2b
Molecular Weight (kDa) 85/515/600 kDA
Notes only use non-reducing conditions for Western blotting
Research Area Epigenetics & Nuclear Signalling, Cell Signaling & Signal Transduction, Neurobiology

References

There are 2 reference entries for this reagent.

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References: 2 entries

Strickland et al. 1990. J Biol Chem. 265(29):17401-4. PMID: 1698775.

Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor.

Europe PMC ID: 1698775


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References: 2 entries

Strickland et al. 1990. J Biol Chem. 265(29):17401-4. PMID: 1698775.

Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor.


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