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Anti-γ-ECS [11H7.C1.A2]

Info

Catalogue Number 153932
Applications ELISA IF WB
Antigen/Gene or Protein Targets Gamma-Glutamylcysteine Synthetase
Synonyms γ-ECS
Reactivity E.coli, Plant and Saccharomyces
Relevance Together with glutathione synthetase and phytochelatin synthetase, gamma-glutamyl Cys sythetase (γ-ECS) is an enzyme involved in, and required for, synthesizing phytochelatins (PC). γ-ECS is involved in the biosynthesis of Glutathione. PC are multidentate ligands that are able to form chelates with thio-reactive, “soft” metal cations such as Cd2+, Hg2+, and at least one oxoanion (AsO33-). In certain plants, deficiency of such enzymes leads to low tolerance to metal contamination while mutants over-expressing them are highly tolerant to metal contamination and may be used in phyto-remediation of heavy metals.
Host Mouse
Immunogen Synthetic peptide
Subclass IgG2a
Notes This mouse IgG2a monoclonal antibody was generated against a synthetic peptide and recognizes E. coli, plants and fission yeast (Schizosaccharomyces pombe ) gamma glutamyl Cys sythetase (γ-ECS), N terminal-MAP. All lines have been validated for use in WB, ELISA, and IF.
Research Area Plant Science, Cell Signaling & Signal Transduction

References

There are 8 reference entries for this reagent.

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References: 8 entries

LeBlanc et al. 2011. Int J Phytoremediation. 13(7):657-73. PMID: 21972493.

Enhanced arsenic tolerance of transgenic eastern cottonwood plants expressing gamma-glutamylcysteine synthetase.

Europe PMC ID: 21972493

Li et al. 2005. Environ Toxicol Chem. 24(6):1376-86. PMID: 16117113.

Arsenic and mercury tolerance and cadmium sensitivity in Arabidopsis plants expressing bacterial gamma-glutamylcysteine synthetase.

Europe PMC ID: 16117113

Dhankher et al. 2002. Nat Biotechnol. 20(11):1140-5. PMID: 12368812.

Engineering tolerance and hyperaccumulation of arsenic in plants by combining arsenate reductase and gamma-glutamylcysteine synthetase expression.

Europe PMC ID: 12368812

Li et al. 2001. Plant Physiol. 127(3):711-9. PMID: 11706154.

Rapid isolation of monoclonal antibodies. Monitoring enzymes in the phytochelatin synthesis pathway.

Europe PMC ID: 11706154


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References: 8 entries

LeBlanc et al. 2011. Int J Phytoremediation. 13(7):657-73. PMID: 21972493.

Enhanced arsenic tolerance of transgenic eastern cottonwood plants expressing gamma-glutamylcysteine synthetase.

Li et al. 2005. Environ Toxicol Chem. 24(6):1376-86. PMID: 16117113.

Arsenic and mercury tolerance and cadmium sensitivity in Arabidopsis plants expressing bacterial gamma-glutamylcysteine synthetase.

Dhankher et al. 2002. Nat Biotechnol. 20(11):1140-5. PMID: 12368812.

Engineering tolerance and hyperaccumulation of arsenic in plants by combining arsenate reductase and gamma-glutamylcysteine synthetase expression.

Li et al. 2001. Plant Physiol. 127(3):711-9. PMID: 11706154.

Rapid isolation of monoclonal antibodies. Monitoring enzymes in the phytochelatin synthesis pathway.


Add a reference

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