Anti-γ-ECS [11H7.C1.A2]
Invented at University of Georgia
- Datasheet
- References (8)
- Inventor Info
Info
| Catalogue Number | 153932 |
| Applications | ELISA IF WB |
| Antigen/Gene or Protein Targets | Gamma-Glutamylcysteine Synthetase |
| Synonyms | γ-ECS |
| Reactivity | E.coli, Plant and Saccharomyces |
| Relevance | Together with glutathione synthetase and phytochelatin synthetase, gamma-glutamyl Cys sythetase (γ-ECS) is an enzyme involved in, and required for, synthesizing phytochelatins (PC). γ-ECS is involved in the biosynthesis of Glutathione. PC are multidentate ligands that are able to form chelates with thio-reactive, “soft” metal cations such as Cd2+, Hg2+, and at least one oxoanion (AsO33-). In certain plants, deficiency of such enzymes leads to low tolerance to metal contamination while mutants over-expressing them are highly tolerant to metal contamination and may be used in phyto-remediation of heavy metals. |
| Host | Mouse |
| Immunogen | Synthetic peptide |
| Subclass | IgG2a |
| Notes | This mouse IgG2a monoclonal antibody was generated against a synthetic peptide and recognizes E. coli, plants and fission yeast (Schizosaccharomyces pombe ) gamma glutamyl Cys sythetase (γ-ECS), N terminal-MAP. All lines have been validated for use in WB, ELISA, and IF. |
| Research Area | Plant Science, Cell Signaling & Signal Transduction |
References: 8 entries
LeBlanc et al. 2011. Int J Phytoremediation. 13(7):657-73. PMID: 21972493.
Enhanced arsenic tolerance of transgenic eastern cottonwood plants expressing gamma-glutamylcysteine synthetase.
Europe PMC ID: 21972493
Li et al. 2005. Environ Toxicol Chem. 24(6):1376-86. PMID: 16117113.
Arsenic and mercury tolerance and cadmium sensitivity in Arabidopsis plants expressing bacterial gamma-glutamylcysteine synthetase.
Europe PMC ID: 16117113
Dhankher et al. 2002. Nat Biotechnol. 20(11):1140-5. PMID: 12368812.
Engineering tolerance and hyperaccumulation of arsenic in plants by combining arsenate reductase and gamma-glutamylcysteine synthetase expression.
Europe PMC ID: 12368812
Li et al. 2001. Plant Physiol. 127(3):711-9. PMID: 11706154.
Rapid isolation of monoclonal antibodies. Monitoring enzymes in the phytochelatin synthesis pathway.
Europe PMC ID: 11706154
Add a reference
References: 8 entries
LeBlanc et al. 2011. Int J Phytoremediation. 13(7):657-73. PMID: 21972493.
Enhanced arsenic tolerance of transgenic eastern cottonwood plants expressing gamma-glutamylcysteine synthetase.
Li et al. 2005. Environ Toxicol Chem. 24(6):1376-86. PMID: 16117113.
Arsenic and mercury tolerance and cadmium sensitivity in Arabidopsis plants expressing bacterial gamma-glutamylcysteine synthetase.
Dhankher et al. 2002. Nat Biotechnol. 20(11):1140-5. PMID: 12368812.
Engineering tolerance and hyperaccumulation of arsenic in plants by combining arsenate reductase and gamma-glutamylcysteine synthetase expression.
Li et al. 2001. Plant Physiol. 127(3):711-9. PMID: 11706154.
Rapid isolation of monoclonal antibodies. Monitoring enzymes in the phytochelatin synthesis pathway.
Add a reference
