Cancer Research Technology
Log in Register
Menu

Anti-TNF-α [9B10]
RECENTLY UPDATED

Invented at University of Georgia

Info

Catalogue Number 153929
Applications
RECENTLY UPDATED
ELISA IP WB
Antigen/Gene or Protein Targets
RECENTLY UPDATED
Tumor Necrosis Factor- alpha
Synonyms
RECENTLY UPDATED
TNF-α
Reactivity
RECENTLY UPDATED
Horse
Relevance
RECENTLY UPDATED
Tumor necrosis factor is a cell signaling protein or cytokine that is involved in inflammation, and specifically one of the proteins in the acute phase reaction. TNF is produced mainly by macrophages but other white cells too. Some of its roles are to induce fever, apoptotic cell death, inhibit tumorigenesis and inflammation. Diseases associated with dysregulation of TNF production include inflammatory bowel disease (IBD), Psoriasis, Alzheimer's and cancer.
Host
RECENTLY UPDATED
Mouse
Immunogen
RECENTLY UPDATED
Protein
Subclass
RECENTLY UPDATED
IgG2b
Notes
RECENTLY UPDATED
Validated for use in WB and ELISA. Some cross-reactivity observed with rHTNFα. None with nETNFß, nMTNFα, rMTNFß and rPTNFα
Research Area
RECENTLY UPDATED
Cell Signaling & Signal Transduction, Apoptosis and Programmed Cell Death

References

There are 2 reference entries for this reagent.

View All References

References: 2 entries
RECENTLY UPDATED

Su et al. 1992. Hybridoma. 11(6):715-27. PMID: 1284121.

Equine tumor necrosis factor alpha: cloning and expression in Escherichia coli, generation of monoclonal antibodies, and development of a sensitive enzyme-linked immunosorbent assay.

Europe PMC ID: 1284121


Add a reference

References: 2 entries
RECENTLY UPDATED

Su et al. 1992. Hybridoma. 11(6):715-27. PMID: 1284121.

Equine tumor necrosis factor alpha: cloning and expression in Escherichia coli, generation of monoclonal antibodies, and development of a sensitive enzyme-linked immunosorbent assay.


Add a reference

Inventor Information

No inventors are currently linked to this reagent.

Add an inventor