Anti-Profilin 4 and 5 (PRF4, PRF5) [mAbPRF45a]
Invented at University of Georgia
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Info
| Catalogue Number | 153914 |
| Applications | IF WB |
| Antigen/Gene or Protein Targets | Profilin 4 and 5 |
| Synonyms | PRF4 and PRF5 |
| Reactivity | Arabidopsis |
| Relevance | Profilin is a low-molecular weight, actin monomer-binding protein that regulates the organization of actin cytoskeleton in eukaryotes. Profilin promotes actin assembly at the barbed end of filaments and causes depolymerization of filaments by binding and sequestering G-actin. Profilin also interacts with several other ligands, such as membrane polyphospho-inositides, short proline rich stretches in proteins, and the Arp 2/3 complex. |
| Host | Mouse |
| Immunogen | Purified plant Profilin 4 |
| Subclass | IgG1 |
| Notes | Lines mAbPRF1a, mabPRF12a, and mAbGPRF45a recognize Profilins 1, 2, 3, 4 and 5 have been validated for use in WB (1 – 2 μg/mL) and IF. PRFs 1-3 are constitutive while PRFs 4 and 5 are pollen-specific. |
| Research Area | Cell Structure and Motility |
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