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Anti-Profilin 4 and 5 (PRF4, PRF5) [mAbPRF45a]

Info

Catalogue Number 153914
Applications IF WB
Antigen/Gene or Protein Targets Profilin 4 and 5
Synonyms PRF4 and PRF5
Reactivity Arabidopsis
Relevance Profilin is a low-molecular weight, actin monomer-binding protein that regulates the organization of actin cytoskeleton in eukaryotes. Profilin promotes actin assembly at the barbed end of filaments and causes depolymerization of filaments by binding and sequestering G-actin. Profilin also interacts with several other ligands, such as membrane polyphospho-inositides, short proline rich stretches in proteins, and the Arp 2/3 complex.
Host Mouse
Immunogen Purified plant Profilin 4
Subclass IgG1
Notes Lines mAbPRF1a, mabPRF12a, and mAbGPRF45a recognize Profilins 1, 2, 3, 4 and 5 have been validated for use in WB (1 – 2 μg/mL) and IF. PRFs 1-3 are constitutive while PRFs 4 and 5 are pollen-specific.
Research Area Cell Structure and Motility

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