Anti-ARP6 [12B2.G4.E2.C4]
Invented at University of Georgia
- Datasheet
- References (10)
- Inventor Info
Info
| Catalogue Number | 153911 |
| Applications | ELISA IF WB |
| Antigen/Gene or Protein Targets | Actin Related Protein 6 |
| Synonyms | ARP6 |
| Relevance | Actin-related proteins (ARPs) are found in the nuclei of all eukaryotic cells, but their functions are generally understood only in the context of their presence in various yeast and animal chromatin-modifying complexes. Arabidopsis ARP8 shows 30 and 29% amino acid identity to yeast actin and Arabidopsis ACT2 in the regions of alignment, respectively. Because it is not closely related to yeast or human ARP8 and shows similar weak homology to yeast ARP8 and ARP9, the Arabidopsis ARP8 is considered a plant-specific orphan ARP. Arabidopsis thaliana ARP6 is a clear homolog of other eukaryotic ARP6s, including Saccharomyces cerevisiae ARP6, which was identified as a component of the SWR1 chromatin remodeling complex. Arabidopsis ARP6 is localized to the nucleus during interphase but dispersed away from the chromosomes during cell division. ARP6 expression was observed in all vegetative tissues as well as in a subset of reproductive tissues. Null mutations in ARP6 caused numerous defects, including altered development of the leaf, inflorescence, and flower as well as reduced female fertility and early flowering in both long- and short-day photoperiods. |
| Host | Mouse |
| Immunogen | Protein |
| Subclass | IgG1 |
| Notes | Lines 12A2.A3.C2 and 12B2.G4.E2.C4 recognize Actin-Related Protein 6 (ARP6) while line 13F10.A4.G6 binds to the C-terminal amino acids of ARP8 and line 12F5.D4.C3 recognizes the N-terminal amino acids of ARP8. |
| Research Area | Cell Structure and Motility |
References: 10 entries
Soubra et al. 2016. World J Urol. 34(9):1229-37. PMID: 26847182.
The diagnostic accuracy of 18F-fluorodeoxyglucose positron emission tomography and computed tomography in staging bladder cancer: a single-institution study and a systematic review with meta-analysis.
Europe PMC ID: 26847182
Kandasamy et al. 2010. Cytoskeleton (Hoboken). 67(11):729-43. PMID: 20862689.
Differential sublocalization of actin variants within the nucleus.
Europe PMC ID: 20862689
Kandasamy et al. 2008. Plant Cell Physiol. 49(5):858-63. PMID: 18385164.
ACTIN-RELATED PROTEIN8 encodes an F-box protein localized to the nucleolus in Arabidopsis.
Europe PMC ID: 18385164
Meagher et al. 2005. Plant Physiol. 139(4):1576-85. PMID: 16339804.
Nuclear actin-related proteins as epigenetic regulators of development.
Europe PMC ID: 16339804
Li et al. 2001. Plant Physiol. 127(3):711-9. PMID: 11706154.
Rapid isolation of monoclonal antibodies. Monitoring enzymes in the phytochelatin synthesis pathway.
Europe PMC ID: 11706154
Add a reference
References: 10 entries
Soubra et al. 2016. World J Urol. 34(9):1229-37. PMID: 26847182.
The diagnostic accuracy of 18F-fluorodeoxyglucose positron emission tomography and computed tomography in staging bladder cancer: a single-institution study and a systematic review with meta-analysis.
Kandasamy et al. 2010. Cytoskeleton (Hoboken). 67(11):729-43. PMID: 20862689.
Differential sublocalization of actin variants within the nucleus.
Kandasamy et al. 2008. Plant Cell Physiol. 49(5):858-63. PMID: 18385164.
ACTIN-RELATED PROTEIN8 encodes an F-box protein localized to the nucleolus in Arabidopsis.
Meagher et al. 2005. Plant Physiol. 139(4):1576-85. PMID: 16339804.
Nuclear actin-related proteins as epigenetic regulators of development.
Li et al. 2001. Plant Physiol. 127(3):711-9. PMID: 11706154.
Rapid isolation of monoclonal antibodies. Monitoring enzymes in the phytochelatin synthesis pathway.
Add a reference
