Anti-O-linked N-acetylglucosamine (O-GlcNAc) [14D9.D4]
RECENTLY UPDATED

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Inventor Info

Info

Catalogue Number	153888
Applications RECENTLY UPDATED	ELISA WB
Antigen/Gene or Protein Targets RECENTLY UPDATED	O-linked N-acetylglucosamine
Synonyms RECENTLY UPDATED	O-GlcNAc
Reactivity RECENTLY UPDATED	Mammals
Relevance RECENTLY UPDATED	The study of O-GlcNAc, a ubiquitous translation and transcription regulator which is found in a wide variety of proteins, is of great relevance to multiple chronic human and veterinary diseases. These include diabetes (and its effects in the heart, kidneys and eyes), cardiovascular disease, neurodegenerative disorders involving both plaque and tangle formation, inflammatory processes, liver disease, fibrosis, metabolic disorders and cancer. There is fast growing collection of evidence that O-GlcNAcylation plays a pivotal role in epigenetics.
Host RECENTLY UPDATED	Mouse
Immunogen RECENTLY UPDATED	Synthetic peptide O-GlcNAc
Subclass RECENTLY UPDATED	IgG2a
Notes RECENTLY UPDATED	This a 23 Mab panel was developed specifically to study the diverse roles of O-GlcNAc and that can be employed for detection, isolation, and site localization. For details on antigen strategy, please consult: Chin Fen Teo, et al., Nat Chem Biol. 2010 May; 6(5): 338-343. doi:10.1038/nchembio.338.
Research Area RECENTLY UPDATED	Cell Signaling & Signal Transduction, Metabolism, Cancer, Epigenetics & Nuclear Signalling, Gene Expression, Neurobiology

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20305658

26822118

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20305658

26822118

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	University of Georgia
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