Anti-Integrin Alpha 2b (GPiib, CD41) [MCB 417.3]
Invented at Versiti Blood Research Institute
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Info
| Catalogue Number | 153806 |
| Applications | FACS IP |
| Antigen/Gene or Protein Targets | Integrin Alpha 2b (GPiib, CD41) |
| Synonyms | CD-41 |
| Reactivity | Mouse |
| Relevance | Glycoprotein IIb/IIIa, also known as integrin aIIbß3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder. |
| Host | Mouse |
| Immunogen | mouse platelet |
| Notes | Domain is B-prop |
| Research Area | Immunology |
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