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IAHF Intralobular Human Fibroblast Cell Line

Invented by Mikkel Morsing, Lone Rønnov-Jessen

Info

Catalogue Number 153783
Synonyms "IAHF Intralobular Human Fibroblast Cell Line", "CD105high/CD26low lobular fibroblasts"
Disease Keywords Breast Cancer
Relevance CD105high/CD26low lobular fibroblasts have been shown to grow in culture maintaining its CD105/CD26 phenotype and functional distinction.
Furthermore, the CD105high/CD26low lobular fibroblasts are distinguished by their capacity to differentiate into adipogenic and osteogenic lineages.

Moreover, upon exposure to serum originally shown to reveal myofibroblastic differentiation in normal breast fibroblasts, the gene expression profile of CD105high/CD26low partly overlaps with the profile of breast tumor stoma.
Research Area Cancer
Notes Keywords: Breast, Epithelial morphogenesis, Fibroblasts, Mesenchymal stem cells

References

There are 2 reference entries for this reagent.

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References: 2 entries

Morsing et al. 2016. Breast Cancer Res. 18(1):108. PMID: 27809866.

Evidence of two distinct functionally specialized fibroblast lineages in breast stroma.

Europe PMC ID: 27809866


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References: 2 entries

Morsing et al. 2016. Breast Cancer Res. 18(1):108. PMID: 27809866.

Evidence of two distinct functionally specialized fibroblast lineages in breast stroma.


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Inventor Information

Inventors

Mikkel Morsing

Mikkel Morsing

Lone Rønnov-Jessen

Lone Rønnov-Jessen

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