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Family 2 father - LAD-III EBV Lymphoblastoid Cell Line

Invented by Prof Nancy Hogg at Cancer Research UK London Research Institute: Lincoln's Inn Fields

Info

Catalogue Number 153768
Antigen/Gene or Protein Targets Kindlin-3, UniProt ID:Q86UX7
Synonyms Fermitin family homolog 3, MIG2-like protein, Unc-112-related protein 2
Host Human
Disease Keywords Leukocyte Adhesion Deficiency-III (LAD-III)
Relevance An EBV-transformed B lymphoblastoid cell line (LCL) derived from the father of a Turkish subject that has Leukocyte Adhesion Deficiency-III (LAD-III) with a mutation in the kindlin-3 gene. LCLs are also available from the subject. This cell line was derived from 'Family 2 father' as described in Svensson et al. 2009. N.Nat Med. 2009 Mar;15(3):306-12. PMID: 19234463
Research Area Adhesion, Cardiovascular, Immunology
Growth/Phenotype Keywords Suspension, lymphoblastoid cell line
Recommended Growing Conditions RPMI-1640 + 10% FCS

References

There are 2 reference entries for this reagent.

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References: 2 entries

Svensson et al. 2009. Nat Med. 15(3):306-12. PMID: 19234463.

Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation.

Europe PMC ID: 19234463


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References: 2 entries

Svensson et al. 2009. Nat Med. 15(3):306-12. PMID: 19234463.

Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation.


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