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Anti-Integrin Beta 3a (GPIIIa, CD61)  [MBC 322.8]

Invented at Versiti Blood Research Institute

Info

Catalogue Number 153749
Applications FACS
Antigen/Gene or Protein Targets Integrin Beta 3a (GPIIIa, CD61) 
Synonyms CD-61
Relevance Glycoprotein IIb/IIIa, also known as integrin aIIbß3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder.
Host Mouse
Immunogen EGF repeats
Subclass IgG1
Molecular Weight (kDa) ~ 86-87 kDa
Notes Ligand Binding Site (LIBS) antibody
Research Area Immunology

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