Anti-Integrin Beta 3a (GPIIIa, CD61) [MBC 322.8]
Invented at Versiti Blood Research Institute
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Info
| Catalogue Number | 153749 |
| Applications | FACS |
| Antigen/Gene or Protein Targets | Integrin Beta 3a (GPIIIa, CD61) |
| Synonyms | CD-61 |
| Relevance | Glycoprotein IIb/IIIa, also known as integrin aIIbß3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder. |
| Host | Mouse |
| Immunogen | EGF repeats |
| Subclass | IgG1 |
| Molecular Weight (kDa) | ~ 86-87 kDa |
| Notes | Ligand Binding Site (LIBS) antibody |
| Research Area | Immunology |
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