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Anti-Integrin Beta 3a (GPIIIa, CD61)  [ AP-5]

Info

Catalogue Number 153747
Applications FACS IHC WB
Antigen/Gene or Protein Targets Integrin Beta 3a (GPIIIa, CD61) 
Synonyms CD-61
Reactivity Human
Relevance Glycoprotein IIb/IIIa, also known as integrin aIIbß3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder.
Host Mouse
Immunogen peptide
Subclass IgG1
Molecular Weight (kDa) ~ 86-87 kDa
Notes Epitope - PSI domain (AA1-6)
Research Area Immunology

References

There are 2 reference entries for this reagent.

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References: 2 entries

Honda et al. 1995. J Biol Chem. 270(20):11947-54. PMID: 7538128.

Topography of ligand-induced binding sites, including a novel cation-sensitive epitope (AP5) at the amino terminus, of the human integrin beta 3 subunit.

Europe PMC ID: 7538128


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References: 2 entries

Honda et al. 1995. J Biol Chem. 270(20):11947-54. PMID: 7538128.

Topography of ligand-induced binding sites, including a novel cation-sensitive epitope (AP5) at the amino terminus, of the human integrin beta 3 subunit.


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