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Anti-Integrin Beta 3 (GPIIIa, CD61)  [AP-2]

Info

Catalogue Number 153745
Applications ELISA FACS
Antigen/Gene or Protein Targets Integrin Beta 3 (GPIIIa, CD61) 
Synonyms CD-61
Relevance Glycoprotein IIb/IIIa, also known as integrin aIIbß3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder.
Host Mouse
Immunogen Human platelet
Subclass IgG1
Research Area Immunology

References

There are 2 reference entries for this reagent.

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References: 2 entries

Pidard et al. 1983. J Biol Chem. 258(20):12582-6. PMID: 6226659.

Interaction of AP-2, a monoclonal antibody specific for the human platelet glycoprotein IIb-IIIa complex, with intact platelets.

Europe PMC ID: 6226659


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References: 2 entries

Pidard et al. 1983. J Biol Chem. 258(20):12582-6. PMID: 6226659.

Interaction of AP-2, a monoclonal antibody specific for the human platelet glycoprotein IIb-IIIa complex, with intact platelets.


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