Anti-Integrin Beta 3 (GPIIIa, CD61) [AP-2]
Invented at Versiti Blood Research Institute
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 153745 |
| Applications | ELISA FACS |
| Antigen/Gene or Protein Targets | Integrin Beta 3 (GPIIIa, CD61) |
| Synonyms | CD-61 |
| Relevance | Glycoprotein IIb/IIIa, also known as integrin aIIbß3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder. |
| Host | Mouse |
| Immunogen | Human platelet |
| Subclass | IgG1 |
| Research Area | Immunology |
References: 2 entries
Pidard et al. 1983. J Biol Chem. 258(20):12582-6. PMID: 6226659.
Interaction of AP-2, a monoclonal antibody specific for the human platelet glycoprotein IIb-IIIa complex, with intact platelets.
Europe PMC ID: 6226659
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References: 2 entries
Pidard et al. 1983. J Biol Chem. 258(20):12582-6. PMID: 6226659.
Interaction of AP-2, a monoclonal antibody specific for the human platelet glycoprotein IIb-IIIa complex, with intact platelets.
Add a reference
