Anti-galβ1-4glcnac epitope [3F11]
Invented by Prof Michael Apicella from The University Of Iowa
Invented at The University Of Iowa
- Datasheet
- References (2)
- Inventor Info
Info
Catalogue Number | 153694 |
Applications | N/A |
Antigen/Gene or Protein Targets | lactosamine (galβ1-4glcnac) epitope found in lipooligosaccharide (LOS) of pathogenic Neisseria species |
Reactivity | Neisseria sp., Neisseria gonorrhoeae and Neisseria meningitidis |
Relevance | Neisseria gonorrhoeae is a human adapted pathogen that infects the reproductive tracts of both male and females causing pelvic inflammatory disease (PID). In females, infection often goes undetected subsequently leading to issues with infertility |
Host | Mouse |
Subclass | IgM |
Notes | N. gonorrhoeae strain 1291 monoclonal antibody. Shown to recognize common antigenic region in gonococcal lipopolysaccharide (LPS). Recognizes conserved region on 6 different different gonococcal serotypes (90% of gonococci can be typed to 1 of these 6 serotypes). Useful for researchers studying function and structure of gonococcal LPS. |
Research Area | Bacteriology, Immunology, Microbiology |
References: 2 entries
Lee et al. 1995. Infect Immun. 63(7):2508-15. PMID: 7790063.
Microheterogeneity of Neisseria lipooligosaccharide: analysis of a UDP-glucose 4-epimerase mutant of Neisseria meningitidis NMB.
Europe PMC ID: 7790063
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References: 2 entries
Lee et al. 1995. Infect Immun. 63(7):2508-15. PMID: 7790063.
Microheterogeneity of Neisseria lipooligosaccharide: analysis of a UDP-glucose 4-epimerase mutant of Neisseria meningitidis NMB.
Add a reference