Anti-galβ1-4glcnac epitope [6B4]
Invented by Prof Michael Apicella from The University Of Iowa
Invented at The University Of Iowa
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 153693 |
| Applications | N/A |
| Antigen/Gene or Protein Targets | lactosamine (galβ1-4glcnac) epitope found in lipooligosaccharide (LOS) of pathogenic Neisseria species |
| Reactivity | Neisseria sp., Neisseria gonorrhoeae and Neisseria meningitidis |
| Relevance | N. gonorrhoeae is a human adapted pathogen that infects the reproductive tracts of both male and females causing pelvic inflammatory disease (PID). In females, infection often goes undetected subsequently leading to issues with infertility |
| Host | Mouse |
| Subclass | IgM kappa |
| Notes | Shown to bind terminal lactosamine (galβ1-4glcnac epitope) sugar in N. gonorrhoeae biofilm. Recognizes conserved LOS epiptope on over 200 gonococcal strains. Useful for researchers studying the biology and pathology of gonococcal infections. |
| Research Area | Bacteriology, Immunology, Microbiology |
References: 2 entries
Greiner et al. 2005. Infect Immun. 73(4):1964-70. PMID: 15784536.
Biofilm Formation by Neisseria gonorrhoeae.
Europe PMC ID: 15784536
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References: 2 entries
Greiner et al. 2005. Infect Immun. 73(4):1964-70. PMID: 15784536.
Biofilm Formation by Neisseria gonorrhoeae.
Add a reference
