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Anti-Omomyc [21-1-3]

Invented by Laura Soucek

Info

Catalogue Number 153657
Applications ELISA IHC IF WB
Antigen/Gene or Protein Targets Omomyc
Reactivity Human
Relevance Omomyc is a dominant-negative allele of the proto-oncogene Myc (c-Myc). Expression of omomyc can induce rapid tumour regression in mouse models with little toxicity for normal tissues.
Host Mouse
Subclass IgG2a kappa
Research Area Apoptosis and Programmed Cell Death, Cancer, Cell Cycle, Gene Expression

References

There are 6 reference entries for this reagent.

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References: 6 entries

Fiorentino et al. 2016. Oncotarget. 7(21):31014-28. PMID: 27105536.

Growth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation.

Europe PMC ID: 27105536

Soucek et al. 2013. Genes Dev. 27(5):504-13. PMID: 23475959.

Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice.

Europe PMC ID: 23475959

Soucek et al. 2004. Cell Death Differ. 11(9):1038-45. PMID: 15143346.

Omomyc expression in skin prevents Myc-induced papillomatosis.

Europe PMC ID: 15143346


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References: 6 entries

Fiorentino et al. 2016. Oncotarget. 7(21):31014-28. PMID: 27105536.

Growth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation.

Soucek et al. 2013. Genes Dev. 27(5):504-13. PMID: 23475959.

Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice.

Soucek et al. 2004. Cell Death Differ. 11(9):1038-45. PMID: 15143346.

Omomyc expression in skin prevents Myc-induced papillomatosis.


Add a reference

Inventor Information