Anti-Adiponectin [399R]
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- References (11)
- Inventor Info
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| Catalogue Number | 153654 |
| Applications | ELISA |
| Antigen/Gene or Protein Targets | Adiponectin |
| Synonyms | Adiponectin, 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, ACRP30, Adipose most abundant gene transcript 1 protein, apM-1, Gelatin-binding protein, ADIPOQ, ACDC, ACRP30, APM1, GBP28 |
| Reactivity | Human |
| Relevance | Adiponectin plays an important role in pathogenesis and amplification of insulin-resistant states in humans, where levels are reduced in patients with type-2 diabetes and obesity. (Hotta K, et al.) Clone 399R is used to detect plasma adiponectin concentrations. Clone 399R is also used in a combination ELISA with clone 32F8, acting as the capture antibody. |
| Host | Mouse |
| Immunogen | Synthetic peptide corresponding to the tail region of the Adiponectin molecule |
| Subclass | IgG1 |
| Myeloma Used | Sp2/0-Ag14 |
| Strain | Balb/c |
| Notes |
Suggested dilutions for use ELISA 1:1000 Research Areas: Cardiovascular;Diabetes |
| Research Area | Cardiovascular, Metabolism |
References: 11 entries
Hazell, M.J. (2009) Development and Clinical Applications of Immunoassays for Human Adiponectin. Thesis. Oxford Brookes University
Miller et al. 2011. Am J Physiol Endocrinol Metab. 301(4):E659-67. PMID: 21750269.
Secretion of adipokines by human adipose tissue in vivo: partitioning between capillary and lymphatic transport.
Europe PMC ID: 21750269
Kiewiet et al. 2011. J Endocrinol Invest. 34(6):434-8. PMID: 20959720.
Acute effects of acylated and unacylated ghrelin on total and high molecular weight adiponectin inmorbidly obese subjects.
Europe PMC ID: 20959720
Sodi et al. 2009. Clin Biochem. 42(13-14):1375-80. PMID: 19523465.
The circulating concentration and ratio of total and high molecular weight adiponectin in post-menopausal women with and without osteoporosis and its association with body mass index and biochemical markers of bone metabolism.
Europe PMC ID: 19523465
Barber et al. 2008. J Clin Endocrinol Metab. 93(7):2859-65. PMID: 18445670.
Serum levels of retinol-binding protein 4 and adiponectin in women with polycystic ovary syndrome: associations with visceral fat but no evidence for fat mass-independent effects on pathogenesis in this condition.
Europe PMC ID: 18445670
Hotta et al. 2000. Arterioscler Thromb Vasc Biol. 20(6):1595-9. PMID: 10845877.
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.
Europe PMC ID: 10845877
Add a reference
References: 11 entries
Hazell, M.J. (2009) Development and Clinical Applications of Immunoassays for Human Adiponectin. Thesis. Oxford Brookes University
Miller et al. 2011. Am J Physiol Endocrinol Metab. 301(4):E659-67. PMID: 21750269.
Secretion of adipokines by human adipose tissue in vivo: partitioning between capillary and lymphatic transport.
Kiewiet et al. 2011. J Endocrinol Invest. 34(6):434-8. PMID: 20959720.
Acute effects of acylated and unacylated ghrelin on total and high molecular weight adiponectin inmorbidly obese subjects.
Sodi et al. 2009. Clin Biochem. 42(13-14):1375-80. PMID: 19523465.
The circulating concentration and ratio of total and high molecular weight adiponectin in post-menopausal women with and without osteoporosis and its association with body mass index and biochemical markers of bone metabolism.
Barber et al. 2008. J Clin Endocrinol Metab. 93(7):2859-65. PMID: 18445670.
Serum levels of retinol-binding protein 4 and adiponectin in women with polycystic ovary syndrome: associations with visceral fat but no evidence for fat mass-independent effects on pathogenesis in this condition.
Hotta et al. 2000. Arterioscler Thromb Vasc Biol. 20(6):1595-9. PMID: 10845877.
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.
Add a reference