Anti-Growth Differentiation Factor 9B [28A]
Invented at
- Datasheet
- References (6)
- Inventor Info
Info
![Clone 28A used to purifiy and quantify human BMP15 by Western Blot. B. The processed mature region of pro-mature BMP15 was quantified by Western blotting [mab28 monoclonal antibody [42]] using the mature region of hBMP15 (R&D Systems) as a standard. Lanes 1–4: mature region of BMP15 (R&D Systems); 200, 100, 50 and 10 ng, respectively. Lanes 5–7: decreasing doses of the purified BMP15 pro-mature complex. Source: Sudiman et al. 2014. PLoS One. 9(7):e103563. PMID: 25058588.](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/bc3a6e2a-9fe5-4268-ad7e-1d9d4dc4753e.png)
![Clone 28A used to purifiy and quantify human BMP15 by Western Blot. B. The processed mature region of pro-mature BMP15 was quantified by Western blotting [mab28 monoclonal antibody [42]] using the mature region of hBMP15 (R&D Systems) as a standard. Lanes 1–4: mature region of BMP15 (R&D Systems); 200, 100, 50 and 10 ng, respectively. Lanes 5–7: decreasing doses of the purified BMP15 pro-mature complex. Source: Sudiman et al. 2014. PLoS One. 9(7):e103563. PMID: 25058588.](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/bc3a6e2a-9fe5-4268-ad7e-1d9d4dc4753e.png)
![Image thumbnail for Anti-Growth Differentiation Factor 9B [28A]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/33d83f20-729a-44a1-a8d1-6fc8f9a52317.png)
![Image thumbnail for Anti-Growth Differentiation Factor 9B [28A]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/a701faf6-32c9-44b9-a6e0-4c78f44b6734.png)
![Image thumbnail for Anti-Growth Differentiation Factor 9B [28A]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/bc3a6e2a-9fe5-4268-ad7e-1d9d4dc4753e.png)
| Catalogue Number | 153650 |
| Applications | ELISA WB |
| Antigen/Gene or Protein Targets | Growth Differentiation Factor 9B |
| Synonyms | Bone morphogenetic protein 15, BMP-15, Growth/differentiation factor 9B, GDF9B |
| Reactivity | Human |
| Relevance | BMP15, also known as GDF9B, plays a crucial role in the regulation of fertility. Clone 28A has been used to detect BMP15 expression and biosynthesis in various carcinoma progression studies. |
| Host | Mouse |
| Immunogen | Recognizes sequence SAEVTASSSKHSGPENNQC on the C-terminus of human GDF9B (BMP15) |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 55 |
| Myeloma Used | Sp2/0-Ag14 |
| Notes |
Suggested dilutions for use Western Blot 1:5000 Immunocytochemistry Assay-dependent ELISA Assay-dependent Immunoblot 1:10000 Research Areas: Endocrinology;Cancer;Fertility;Developmental Biology |
| Research Area | Cancer, Developmental Biology |
References: 6 entries
Bone morphogenetic protein 15 in the pro-mature complex form enhances bovine oocyte developmental competence.
Europe PMC ID: 25058588
Sudiman et al. 2014. PLoS One. 9(7):e103563. PMID: 25058588.
Al-Musawi et al. 2013. Endocrinology. 154(2):888-99. PMID: 23284103.
Species differences in the expression and activity of bone morphogenetic protein 15.
Europe PMC ID: 23284103
Pulkki et al. 2011. Mol Cell Endocrinol. 332(1-2):106-15. PMID: 20937357.
The bioactivity of human bone morphogenetic protein-15 is sensitive to C-terminal modification: characterization of the purified untagged processed mature region.
Europe PMC ID: 20937357
Add a reference
References: 6 entries
Bone morphogenetic protein 15 in the pro-mature complex form enhances bovine oocyte developmental competence.
Sudiman et al. 2014. PLoS One. 9(7):e103563. PMID: 25058588.
Al-Musawi et al. 2013. Endocrinology. 154(2):888-99. PMID: 23284103.
Species differences in the expression and activity of bone morphogenetic protein 15.
Pulkki et al. 2011. Mol Cell Endocrinol. 332(1-2):106-15. PMID: 20937357.
The bioactivity of human bone morphogenetic protein-15 is sensitive to C-terminal modification: characterization of the purified untagged processed mature region.
Add a reference