Anti-Inhibin α [PO12/8]
Invented at
- Datasheet
- References (6)
- Inventor Info
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| Catalogue Number | 153647 |
| Applications | ELISA IHC |
| Antigen/Gene or Protein Targets | Inhibin α |
| Synonyms | Inhibin alpha chain, INHA |
| Reactivity | Human |
| Relevance | Higher levels of inhibin α have been associated with a higher risk of cancer progression and recurrence. Clone PO 12/8 is useful in detecting inhibin α levels, especially in prostate cancer cells. |
| Host | Mouse |
| Immunogen | Synthetic peptide corresponding to epitope region aa73-96 of the αC region of α subunit of inhibin A |
| Positive Control | Prostate tissue |
| Subclass | IgG2a |
| Molecular Weight (kDa) | 40 |
| Myeloma Used | Sp2/0-Ag14 |
| Strain | Balb/c |
| Notes |
Suggested dilutions for use Immunohistochemistry 90 μg/ml ELISA Assay-dependent Research Areas: Endocrinology;Cancer;Fertility;Cell Signaling & Signal Transduction |
| Research Area | Cancer, Cell Signaling & Signal Transduction |
References: 6 entries
Balanathan et al. 2009. Br J Cancer. 100(11):1784-93. PMID: 19436293.
Elevated level of inhibin-alpha subunit is pro-tumourigenic and pro-metastatic and associated with extracapsular spread in advanced prostate cancer.
Europe PMC ID: 19436293
Risbridger et al. 2004. Mol Cell Endocrinol. 225(1-2):73-6. PMID: 15451570.
Re-evaluation of inhibin alpha subunit as a tumour suppressor in prostate cancer.
Europe PMC ID: 15451570
Robertson et al. 2001. Mol Cell Endocrinol. 180(1-2):79-86. PMID: 11451575.
Development of an inhibin alpha subunit ELISA with broad specificity.
Europe PMC ID: 11451575
Add a reference
References: 6 entries
Balanathan et al. 2009. Br J Cancer. 100(11):1784-93. PMID: 19436293.
Elevated level of inhibin-alpha subunit is pro-tumourigenic and pro-metastatic and associated with extracapsular spread in advanced prostate cancer.
Risbridger et al. 2004. Mol Cell Endocrinol. 225(1-2):73-6. PMID: 15451570.
Re-evaluation of inhibin alpha subunit as a tumour suppressor in prostate cancer.
Robertson et al. 2001. Mol Cell Endocrinol. 180(1-2):79-86. PMID: 11451575.
Development of an inhibin alpha subunit ELISA with broad specificity.
Add a reference