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Anti-Protein Kinase C α [133]

Info

Catalogue Number 153646
Applications IHC WB
Antigen/Gene or Protein Targets Protein Kinase C α
Synonyms Protein kinase C alpha,
PKC-A, PKC-alpha, PRKCA, PKCA, PRKACA
Reactivity Human and Mammals
Relevance Protein Kinase C alpha (PKCα) is involved in the regulation of cell proliferation during cell cycle progression. Clone 133 recognizes the α isoform of PKCα and binds to a sequence at the C terminus of PKCα to detect its expression in vitro.
Host Mouse
Immunogen Recognizes sequence PQFVHPILQSAV at the C terminus at PKCα
Positive Control Retina
Subclass IgG2a
Molecular Weight (kDa) 75
Myeloma Used Sp2/0-Ag14
Strain Balb/c
Notes Suggested dilutions for use

Western Blot 1:10-1:500
Immunohistochemistry 1:10

Research Areas: Cancer; Neurobiology; Pathology; Cell Biology
Research Area Cancer, Neurobiology

References

There are 8 reference entries for this reagent.

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References: 8 entries

Donovan et al. 2012. Mol Pharmacol. 82(3):428-37. PMID: 22653970.

Long QT2 mutation on the Kv11.1 ion channel inhibits current activity by ablating a protein kinase Cα consensus site.

Europe PMC ID: 22653970

Cao et al. 2012. Proc Natl Acad Sci U S A. 109(20):7905-10. PMID: 22547806.

Regulators of G protein signaling RGS7 and RGS11 determine the onset of the light response in ON bipolar neurons.

Europe PMC ID: 22547806

Campo et al. 2010. Biochim Biophys Acta. 1802(11):1118-30. PMID: 20713153.

High-molecular weight hyaluronan reduced renal PKC activation in genetically diabetic mice.

Europe PMC ID: 20713153

Huang et al. 2009. Vis Neurosci. 26(5-6):443-52. PMID: 20003598.

Cell type-specific and light-dependent expression of Rab1 and Rab6 GTPases in mammalian retinas.

Europe PMC ID: 20003598


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References: 8 entries

Donovan et al. 2012. Mol Pharmacol. 82(3):428-37. PMID: 22653970.

Long QT2 mutation on the Kv11.1 ion channel inhibits current activity by ablating a protein kinase Cα consensus site.

Cao et al. 2012. Proc Natl Acad Sci U S A. 109(20):7905-10. PMID: 22547806.

Regulators of G protein signaling RGS7 and RGS11 determine the onset of the light response in ON bipolar neurons.

Campo et al. 2010. Biochim Biophys Acta. 1802(11):1118-30. PMID: 20713153.

High-molecular weight hyaluronan reduced renal PKC activation in genetically diabetic mice.

Huang et al. 2009. Vis Neurosci. 26(5-6):443-52. PMID: 20003598.

Cell type-specific and light-dependent expression of Rab1 and Rab6 GTPases in mammalian retinas.


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