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Anti-Deleted in azoospermia-like [DAZL3/11A]

Info

Catalogue Number 153645
Applications IHC IF WB
Antigen/Gene or Protein Targets Deleted in azoospermia-like
Synonyms Deleted in azoospermia-like, DAZL, DAZ homolog, DAZ-like autosomal, Deleted in azoospermia-like 1, SPGY-like-autosomal, DAZH, DAZL1, DAZLA, SPGYLA
Reactivity Human, Mouse, Rat and Cynomolgus monkey
Relevance Deleted in Azoospermia-like (DAZL) protein plays a role in germ cell development. Mutations in this gene are linked to spermatogenic failure and infertility in males. Clone 3/11A recognizes DAZL at its C terminus, and is used in detection of DAZL expression by various methods.
Host Mouse
Immunogen Recognizes DAZL protein C terminus sequence CRVHHFRRSRAMLKSV
Positive Control Testis or Ovary
Subclass IgG1
Molecular Weight (kDa) 33
Myeloma Used Sp2/0-Ag14
Notes Suggested dilutions for use

Western Blot 1:100-1:1000
Immunohistochemistry 1:50-1:500
Immunofluorescence 1:50-1:500

Research Areas: Endocrinology;Fertility;Genetics;Developmental Biology;Stem Cell Biology
Research Area Developmental Biology, Stem Cell Biology

References

There are 10 reference entries for this reagent.

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References: 10 entries

GDF9 is transiently expressed in oocytes before follicle formation in the human fetal ovary and is regulated by a novel NOBOX transcript.

Europe PMC ID: 25790371

Bayne et al. 2015. PLoS One. 10(3):e0119819. PMID: 25790371.

Dynamic changes in DNA modification states during late gestation male germ line development in the rat.

Europe PMC ID: 25225576

Rose et al. 2014. Epigenetics Chromatin. 7:19. PMID: 25225576.

Chen et al. 2013. BMC Biol. 11:22. PMID: 23497137.

Disruption of genital ridge development causes aberrant primordial germ cell proliferation but does not affect their directional migration.

Europe PMC ID: 23497137

In vitro germ cell differentiation from cynomolgus monkey embryonic stem cells.

Europe PMC ID: 19399191

Yamauchi et al. 2009. PLoS One. 4(4):e5338. PMID: 19399191.

Anderson et al. 2007. BMC Dev Biol. 7:136. PMID: 18088417.

Conserved and divergent patterns of expression of DAZL, VASA and OCT4 in the germ cells of the human fetal ovary and testis.

Europe PMC ID: 18088417


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References: 10 entries

GDF9 is transiently expressed in oocytes before follicle formation in the human fetal ovary and is regulated by a novel NOBOX transcript.

Bayne et al. 2015. PLoS One. 10(3):e0119819. PMID: 25790371.

Dynamic changes in DNA modification states during late gestation male germ line development in the rat.

Rose et al. 2014. Epigenetics Chromatin. 7:19. PMID: 25225576.

Chen et al. 2013. BMC Biol. 11:22. PMID: 23497137.

Disruption of genital ridge development causes aberrant primordial germ cell proliferation but does not affect their directional migration.

In vitro germ cell differentiation from cynomolgus monkey embryonic stem cells.

Yamauchi et al. 2009. PLoS One. 4(4):e5338. PMID: 19399191.

Anderson et al. 2007. BMC Dev Biol. 7:136. PMID: 18088417.

Conserved and divergent patterns of expression of DAZL, VASA and OCT4 in the germ cells of the human fetal ovary and testis.


Add a reference

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