Anti-Myelin Basic Protein (region 36-50) [MBP14]
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- Datasheet
- References (10)
- Inventor Info
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| Catalogue Number | 153642 |
| Applications | ELISA IHC IF WB |
| Antigen/Gene or Protein Targets | Myelin Basic Protein (region 36-50) |
| Synonyms |
Myelin basic protein, MBP, 20 kDa microtubule-stabilizing protein, Myelin A1 protein |
| Reactivity | Bovine, Chicken, Horse and Human |
| Relevance | Myelin Basic Protein (MBP) is involved in the process of myelination of nerves in the nervous system. MBP Clone 14 recognizes an epitope in the 36-50 region of MBP, useful in clinical diagnosis to detect MBP levels or myelination in human MBP. |
| Host | Rat |
| Immunogen | Reacts with human MBP, recognizing epitopes in the 36-50 amino acid region (GILDSIGRFFGGDRG) |
| Positive Control | Brain tissue |
| Subclass | IgG2b |
| Molecular Weight (kDa) | 13-21 |
| Myeloma Used | NS0 |
| Notes |
Suggested dilutions for use Western Blot 1:500 Immunohistochemistry 1:100,000 ELISA 1:2000 Immunofluorescence 1:50 Immunocytochemistry 1:50 Research Areas: Neurobiology; Cell Type or Organelle Marker; Immunology; Endocrinology; Fertility; Genetics |
| Research Area | Cell Type or Organelle Marker, Immunology, Neurobiology |
References: 10 entries
Friess et al. 2016. Cell Calcium. 60(5):322-330. PMID: 27417499.
Intracellular ion signaling influences myelin basic protein synthesis in oligodendrocyte precursor cells.
Europe PMC ID: 27417499
Jackson et al. 2004. Eur J Neurosci. 20(9):2267-75. PMID: 15525268.
Cannabinoid-mediated neuroprotection following interferon-gamma treatment in a three-dimensional mouse brain aggregate cell culture.
Europe PMC ID: 15525268
Matsuo et al. 1997. Am J Pathol. 150(4):1253-66. PMID: 9094982.
Unmasking of an unusual myelin basic protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of autoantigens.
Europe PMC ID: 9094982
Groome et al. 1988. J Neuroimmunol. 19(4):305-15. PMID: 2459156.
New monoclonal antibodies reactive with defined sequential epitopes in human myelin basic protein.
Europe PMC ID: 2459156
Glynn et al. 1987. J Neurochem. 48(3):752-9. PMID: 2433395.
Basic protein dissociating from myelin membranes at physiological ionic strength and pH is cleaved into three major fragments.
Europe PMC ID: 2433395
Add a reference
References: 10 entries
Friess et al. 2016. Cell Calcium. 60(5):322-330. PMID: 27417499.
Intracellular ion signaling influences myelin basic protein synthesis in oligodendrocyte precursor cells.
Jackson et al. 2004. Eur J Neurosci. 20(9):2267-75. PMID: 15525268.
Cannabinoid-mediated neuroprotection following interferon-gamma treatment in a three-dimensional mouse brain aggregate cell culture.
Matsuo et al. 1997. Am J Pathol. 150(4):1253-66. PMID: 9094982.
Unmasking of an unusual myelin basic protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of autoantigens.
Groome et al. 1988. J Neuroimmunol. 19(4):305-15. PMID: 2459156.
New monoclonal antibodies reactive with defined sequential epitopes in human myelin basic protein.
Glynn et al. 1987. J Neurochem. 48(3):752-9. PMID: 2433395.
Basic protein dissociating from myelin membranes at physiological ionic strength and pH is cleaved into three major fragments.
Add a reference