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Anti-Myelin Basic Protein (region 36-50) [MBP14]

Info

Catalogue Number 153642
Applications ELISA IHC IF WB
Antigen/Gene or Protein Targets Myelin Basic Protein (region 36-50)
Synonyms Myelin basic protein,
MBP, 20 kDa microtubule-stabilizing protein, Myelin A1 protein
Reactivity Bovine, Chicken, Horse and Human
Relevance Myelin Basic Protein (MBP) is involved in the process of myelination of nerves in the nervous system. MBP Clone 14 recognizes an epitope in the 36-50 region of MBP, useful in clinical diagnosis to detect MBP levels or myelination in human MBP.
Host Rat
Immunogen Reacts with human MBP, recognizing epitopes in the 36-50 amino acid region (GILDSIGRFFGGDRG)
Subclass IgG2b
Positive Control Brain tissue
Molecular Weight (kDa) 13-21
Myeloma Used NS0
Notes Suggested dilutions for use

Western Blot 1:500
Immunohistochemistry 1:100,000
ELISA 1:2000
Immunofluorescence 1:50
Immunocytochemistry 1:50

Research Areas: Neurobiology; Cell Type or Organelle Marker; Immunology; Endocrinology; Fertility; Genetics
Research Area Cell Type or Organelle Marker, Immunology, Neurobiology

References: 10 entries

Friess et al. 2016. Cell Calcium. 60(5):322-330. PMID: 27417499.

Intracellular ion signaling influences myelin basic protein synthesis in oligodendrocyte precursor cells.

Europe PMC ID: 27417499

Jackson et al. 2004. Eur J Neurosci. 20(9):2267-75. PMID: 15525268.

Cannabinoid-mediated neuroprotection following interferon-gamma treatment in a three-dimensional mouse brain aggregate cell culture.

Europe PMC ID: 15525268

Matsuo et al. 1997. Am J Pathol. 150(4):1253-66. PMID: 9094982.

Unmasking of an unusual myelin basic protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of autoantigens.

Europe PMC ID: 9094982

Groome et al. 1988. J Neuroimmunol. 19(4):305-15. PMID: 2459156.

New monoclonal antibodies reactive with defined sequential epitopes in human myelin basic protein.

Europe PMC ID: 2459156

Glynn et al. 1987. J Neurochem. 48(3):752-9. PMID: 2433395.

Basic protein dissociating from myelin membranes at physiological ionic strength and pH is cleaved into three major fragments.

Europe PMC ID: 2433395


Add a reference

References: 10 entries

Friess et al. 2016. Cell Calcium. 60(5):322-330. PMID: 27417499.

Intracellular ion signaling influences myelin basic protein synthesis in oligodendrocyte precursor cells.

Europe PMC ID: 27417499

Jackson et al. 2004. Eur J Neurosci. 20(9):2267-75. PMID: 15525268.

Cannabinoid-mediated neuroprotection following interferon-gamma treatment in a three-dimensional mouse brain aggregate cell culture.

Europe PMC ID: 15525268

Matsuo et al. 1997. Am J Pathol. 150(4):1253-66. PMID: 9094982.

Unmasking of an unusual myelin basic protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of autoantigens.

Europe PMC ID: 9094982

Groome et al. 1988. J Neuroimmunol. 19(4):305-15. PMID: 2459156.

New monoclonal antibodies reactive with defined sequential epitopes in human myelin basic protein.

Europe PMC ID: 2459156

Glynn et al. 1987. J Neurochem. 48(3):752-9. PMID: 2433395.

Basic protein dissociating from myelin membranes at physiological ionic strength and pH is cleaved into three major fragments.

Europe PMC ID: 2433395


Add a reference

References: 10 entries

Friess et al. 2016. Cell Calcium. 60(5):322-330. PMID: 27417499.

Intracellular ion signaling influences myelin basic protein synthesis in oligodendrocyte precursor cells.

Jackson et al. 2004. Eur J Neurosci. 20(9):2267-75. PMID: 15525268.

Cannabinoid-mediated neuroprotection following interferon-gamma treatment in a three-dimensional mouse brain aggregate cell culture.

Matsuo et al. 1997. Am J Pathol. 150(4):1253-66. PMID: 9094982.

Unmasking of an unusual myelin basic protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of autoantigens.

Groome et al. 1988. J Neuroimmunol. 19(4):305-15. PMID: 2459156.

New monoclonal antibodies reactive with defined sequential epitopes in human myelin basic protein.

Glynn et al. 1987. J Neurochem. 48(3):752-9. PMID: 2433395.

Basic protein dissociating from myelin membranes at physiological ionic strength and pH is cleaved into three major fragments.


Add a reference


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