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Anti-Myelin Basic Protein (region 119-131) [MBP2]

Invented at

Info

Catalogue Number 153639
Applications ELISA IHC IF IP WB
Antigen/Gene or Protein Targets Myelin Basic Protein (region 119-131)
Synonyms Myelin basic protein,
MBP, 20 kDa microtubule-stabilizing protein, Myelin A1 protein
Reactivity Bovine, Human, Guinea Pig, Pig, Rat, Rabbit and Sheep
Relevance Myelin Basic Protein (MBP) is involved in the process of myelination of nerves in the nervous system. MBP Clone 2 recognizes an epitope in the 119-131 region of MBP, useful in clinical diagnosis to detect MBP levels in human, rat and cow MBP.
Host Mouse
Immunogen Recognises bovine MBP, in the region of residues 119-131 (GAEGQRPGFGYGG)
Positive Control Brain tissue
Subclass IgG1
Molecular Weight (kDa) 13-21
Myeloma Used NS0
Notes Suggested dilutions for use

Western Blot 1:10-1:200
Immunohistochemistry 1:75-1:500
Immunoprecipetation 10-20 μL/ 100-500 μg
Immunofluorescence 1:10 – 1:200
ELISA 1:1000

Research Areas: Neurobiology; Cell Type or Organelle Marker;Immunology;Haematology;Genetics;Infectious diseases
Research Area Cell Type or Organelle Marker, Immunology, Neurobiology

References

There are 24 reference entries for this reagent.

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References: 24 entries

Subjects harboring presenilin familial Alzheimer's disease mutations exhibit diverse white matter biochemistry alterations.

Europe PMC ID: 24093083

Kokjohn et al. 2013. J Neurotrauma. 30(11):981-97. PMID: 23268705.

Neurochemical profile of dementia pugilistica.

Europe PMC ID: 23268705

Wong et al. 2013. J Neurosci. 33(11):4947-57. PMID: 23486965.

Oligodendroglial expression of TrkB independently regulates myelination and progenitor cell proliferation.

Europe PMC ID: 23486965

Roher et al. 2013. Am J Neurodegener Dis. 2(3):187-207. PMID: 24093083.

Purkinje cell maturation participates in the control of oligodendrocyte differentiation: role of sonic hedgehog and vitronectin.

Europe PMC ID: 23155445

Tatalovic et al. 2012. Neurosci Lett. 520(1):38-42. PMID: 22617008.

Expression of the P/Q (Cav2.1) calcium channel in nodose sensory neurons and arterial baroreceptors.

Europe PMC ID: 22617008

Bouslama-Oueghlani et al. 2012. PLoS One. 7(11):e49015. PMID: 23155445.

Solbrig et al. 2010. Exp Neurol. 226(1):231-41. PMID: 20832403.

Herrera et al. 2010. J Neurotrauma. 27(11):2067-76. PMID: 20799882.

Sustained expression of vascular endothelial growth factor and angiopoietin-1 improves blood-spinal cord barrier integrity and functional recovery after spinal cord injury.

Europe PMC ID: 20799882

A synthetic cannabinoid agonist promotes oligodendrogliogenesis during viral encephalitis in rats.

Europe PMC ID: 20832403

Schelshorn et al. 2009. J Cereb Blood Flow Metab. 29(3):585-95. PMID: 19116637.

Expression of hemoglobin in rodent neurons.

Europe PMC ID: 19116637

Matsuo et al. 1997. Am J Pathol. 150(4):1253-66. PMID: 9094982.

Unmasking of an unusual myelin basic protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of autoantigens.

Europe PMC ID: 9094982

Hruby et al. 1987. Mol Immunol. 24(12):1359-64. PMID: 2448611.

Monoclonal antibodies reactive with myelin basic protein.

Europe PMC ID: 2448611

Groome et al. 1986. J Neuroimmunol. 12(4):253-64. PMID: 2428830.

Region-specific immunoassays for human myelin basic protein.

Europe PMC ID: 2428830

Groome et al. 1985. Neurochem Int. 7(2):309-17. PMID: 20492929.

Preparation and properties of monoclonal antibodies to myelin basic protein and its peptides.

Europe PMC ID: 20492929


Add a reference

References: 24 entries

Subjects harboring presenilin familial Alzheimer's disease mutations exhibit diverse white matter biochemistry alterations.

Kokjohn et al. 2013. J Neurotrauma. 30(11):981-97. PMID: 23268705.

Neurochemical profile of dementia pugilistica.

Wong et al. 2013. J Neurosci. 33(11):4947-57. PMID: 23486965.

Oligodendroglial expression of TrkB independently regulates myelination and progenitor cell proliferation.

Roher et al. 2013. Am J Neurodegener Dis. 2(3):187-207. PMID: 24093083.

Purkinje cell maturation participates in the control of oligodendrocyte differentiation: role of sonic hedgehog and vitronectin.

Tatalovic et al. 2012. Neurosci Lett. 520(1):38-42. PMID: 22617008.

Expression of the P/Q (Cav2.1) calcium channel in nodose sensory neurons and arterial baroreceptors.

Bouslama-Oueghlani et al. 2012. PLoS One. 7(11):e49015. PMID: 23155445.

Solbrig et al. 2010. Exp Neurol. 226(1):231-41. PMID: 20832403.

Herrera et al. 2010. J Neurotrauma. 27(11):2067-76. PMID: 20799882.

Sustained expression of vascular endothelial growth factor and angiopoietin-1 improves blood-spinal cord barrier integrity and functional recovery after spinal cord injury.

A synthetic cannabinoid agonist promotes oligodendrogliogenesis during viral encephalitis in rats.

Schelshorn et al. 2009. J Cereb Blood Flow Metab. 29(3):585-95. PMID: 19116637.

Expression of hemoglobin in rodent neurons.

Matsuo et al. 1997. Am J Pathol. 150(4):1253-66. PMID: 9094982.

Unmasking of an unusual myelin basic protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of autoantigens.

Hruby et al. 1987. Mol Immunol. 24(12):1359-64. PMID: 2448611.

Monoclonal antibodies reactive with myelin basic protein.

Groome et al. 1986. J Neuroimmunol. 12(4):253-64. PMID: 2428830.

Region-specific immunoassays for human myelin basic protein.

Groome et al. 1985. Neurochem Int. 7(2):309-17. PMID: 20492929.

Preparation and properties of monoclonal antibodies to myelin basic protein and its peptides.


Add a reference

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