Anti-Myelin Basic Protein (region 119-131) [MBP2]
Invented at
- Datasheet
- References (24)
- Inventor Info
Info
![Image thumbnail for Anti-Myelin Basic Protein (region 119-131) [MBP2]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/493232c9-8506-4b67-b951-757a52047467.png)
![Image thumbnail for Anti-Myelin Basic Protein (region 119-131) [MBP2]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/af5f42f2-2051-41ab-a351-7f59d58d8394.png)
![Image thumbnail for Anti-Myelin Basic Protein (region 119-131) [MBP2]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/80900fb5-2165-4586-8a8d-1421d4a5d773.png)
![Image thumbnail for Anti-Myelin Basic Protein (region 119-131) [MBP2]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/f6b5ef60-933d-4bf9-b158-2cea380643ea.png)
![Image thumbnail for Anti-Myelin Basic Protein (region 119-131) [MBP2]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/6346c89c-1d72-48a7-8a62-ec8d711fdc14.png)
| Catalogue Number | 153639 |
| Applications | ELISA IHC IF IP WB |
| Antigen/Gene or Protein Targets | Myelin Basic Protein (region 119-131) |
| Synonyms |
Myelin basic protein, MBP, 20 kDa microtubule-stabilizing protein, Myelin A1 protein |
| Reactivity | Bovine, Human, Guinea Pig, Pig, Rat, Rabbit and Sheep |
| Relevance | Myelin Basic Protein (MBP) is involved in the process of myelination of nerves in the nervous system. MBP Clone 2 recognizes an epitope in the 119-131 region of MBP, useful in clinical diagnosis to detect MBP levels in human, rat and cow MBP. |
| Host | Mouse |
| Immunogen | Recognises bovine MBP, in the region of residues 119-131 (GAEGQRPGFGYGG) |
| Positive Control | Brain tissue |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 13-21 |
| Myeloma Used | NS0 |
| Notes |
Suggested dilutions for use Western Blot 1:10-1:200 Immunohistochemistry 1:75-1:500 Immunoprecipetation 10-20 μL/ 100-500 μg Immunofluorescence 1:10 – 1:200 ELISA 1:1000 Research Areas: Neurobiology; Cell Type or Organelle Marker;Immunology;Haematology;Genetics;Infectious diseases |
| Research Area | Cell Type or Organelle Marker, Immunology, Neurobiology |
References: 24 entries
Subjects harboring presenilin familial Alzheimer's disease mutations exhibit diverse white matter biochemistry alterations.
Europe PMC ID: 24093083
Kokjohn et al. 2013. J Neurotrauma. 30(11):981-97. PMID: 23268705.
Neurochemical profile of dementia pugilistica.
Europe PMC ID: 23268705
Wong et al. 2013. J Neurosci. 33(11):4947-57. PMID: 23486965.
Oligodendroglial expression of TrkB independently regulates myelination and progenitor cell proliferation.
Europe PMC ID: 23486965
Roher et al. 2013. Am J Neurodegener Dis. 2(3):187-207. PMID: 24093083.
Purkinje cell maturation participates in the control of oligodendrocyte differentiation: role of sonic hedgehog and vitronectin.
Europe PMC ID: 23155445
Tatalovic et al. 2012. Neurosci Lett. 520(1):38-42. PMID: 22617008.
Expression of the P/Q (Cav2.1) calcium channel in nodose sensory neurons and arterial baroreceptors.
Europe PMC ID: 22617008
Bouslama-Oueghlani et al. 2012. PLoS One. 7(11):e49015. PMID: 23155445.
Solbrig et al. 2010. Exp Neurol. 226(1):231-41. PMID: 20832403.
Herrera et al. 2010. J Neurotrauma. 27(11):2067-76. PMID: 20799882.
Sustained expression of vascular endothelial growth factor and angiopoietin-1 improves blood-spinal cord barrier integrity and functional recovery after spinal cord injury.
Europe PMC ID: 20799882
A synthetic cannabinoid agonist promotes oligodendrogliogenesis during viral encephalitis in rats.
Europe PMC ID: 20832403
Schelshorn et al. 2009. J Cereb Blood Flow Metab. 29(3):585-95. PMID: 19116637.
Expression of hemoglobin in rodent neurons.
Europe PMC ID: 19116637
Matsuo et al. 1997. Am J Pathol. 150(4):1253-66. PMID: 9094982.
Unmasking of an unusual myelin basic protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of autoantigens.
Europe PMC ID: 9094982
Hruby et al. 1987. Mol Immunol. 24(12):1359-64. PMID: 2448611.
Monoclonal antibodies reactive with myelin basic protein.
Europe PMC ID: 2448611
Groome et al. 1986. J Neuroimmunol. 12(4):253-64. PMID: 2428830.
Region-specific immunoassays for human myelin basic protein.
Europe PMC ID: 2428830
Groome et al. 1985. Neurochem Int. 7(2):309-17. PMID: 20492929.
Preparation and properties of monoclonal antibodies to myelin basic protein and its peptides.
Europe PMC ID: 20492929
Add a reference
References: 24 entries
Subjects harboring presenilin familial Alzheimer's disease mutations exhibit diverse white matter biochemistry alterations.
Kokjohn et al. 2013. J Neurotrauma. 30(11):981-97. PMID: 23268705.
Neurochemical profile of dementia pugilistica.
Wong et al. 2013. J Neurosci. 33(11):4947-57. PMID: 23486965.
Oligodendroglial expression of TrkB independently regulates myelination and progenitor cell proliferation.
Roher et al. 2013. Am J Neurodegener Dis. 2(3):187-207. PMID: 24093083.
Purkinje cell maturation participates in the control of oligodendrocyte differentiation: role of sonic hedgehog and vitronectin.
Tatalovic et al. 2012. Neurosci Lett. 520(1):38-42. PMID: 22617008.
Expression of the P/Q (Cav2.1) calcium channel in nodose sensory neurons and arterial baroreceptors.
Bouslama-Oueghlani et al. 2012. PLoS One. 7(11):e49015. PMID: 23155445.
Solbrig et al. 2010. Exp Neurol. 226(1):231-41. PMID: 20832403.
Herrera et al. 2010. J Neurotrauma. 27(11):2067-76. PMID: 20799882.
Sustained expression of vascular endothelial growth factor and angiopoietin-1 improves blood-spinal cord barrier integrity and functional recovery after spinal cord injury.
A synthetic cannabinoid agonist promotes oligodendrogliogenesis during viral encephalitis in rats.
Schelshorn et al. 2009. J Cereb Blood Flow Metab. 29(3):585-95. PMID: 19116637.
Expression of hemoglobin in rodent neurons.
Matsuo et al. 1997. Am J Pathol. 150(4):1253-66. PMID: 9094982.
Unmasking of an unusual myelin basic protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of autoantigens.
Hruby et al. 1987. Mol Immunol. 24(12):1359-64. PMID: 2448611.
Monoclonal antibodies reactive with myelin basic protein.
Groome et al. 1986. J Neuroimmunol. 12(4):253-64. PMID: 2428830.
Region-specific immunoassays for human myelin basic protein.
Groome et al. 1985. Neurochem Int. 7(2):309-17. PMID: 20492929.
Preparation and properties of monoclonal antibodies to myelin basic protein and its peptides.
Add a reference