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Anti-Estrogen Receptor ß5 [PPG5/25]

Info

Catalogue Number 153633
Applications IHC IF WB
Antigen/Gene or Protein Targets Estrogen Receptor β 5
Synonyms Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2
Reactivity Human
Relevance Estrogen receptors are commonly over-expressed in cancers. Clone PPG5/25 recognizes Estrogen Receptor Beta (ERβ) 5 and is useful in determining the expression of ERβ5 in cancer cells, mainly via immunohistochemistry.
Host Mouse
Immunogen Tuberculin conjugated peptide that recognizes C terminus of ERβ5 at sequence LLSHVRHARYAP
Positive Control Normal colon or colon carcinoma
Subclass IgG1
Myeloma Used Sp2/0-Ag14
Notes Suggested dilutions for use

Western Blot Assay-dependent
Immunohistochemistry 1:50-1:100
Immunofluorescence 1:500

Research Areas: Endocrinology;Cancer;Immunology;Neurobiology;Hepatology
Research Area Cancer, Immunology, Neurobiology

References

There are 10 reference entries for this reagent.

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References: 10 entries

Zannoni et al. 2016. Histopathology. 68(4):541-8. PMID: 26132417.

Li et al. 2015. Oncol Lett. 10(4):2341-2346. PMID: 26622848.

Sexual dimorphism in medulloblastoma features.

Europe PMC ID: 26132417

Cytoplasm estrogen receptor β5 as an improved prognostic factor in thymoma and thymic carcinoma progression.

Europe PMC ID: 26622848

Gender effect in experimental models of human medulloblastoma: does the estrogen receptor β signaling play a role?

Europe PMC ID: 25000562

Ciucci et al. 2014. PLoS One. 9(7):e101623. PMID: 25000562.

Collins et al. 2009. BMC Cancer. 9:330. PMID: 19758455.

Expression of oestrogen receptors, ERalpha, ERbeta, and ERbeta variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERalpha.

Europe PMC ID: 19758455

Wong et al. 2005. J Pathol. 207(1):53-60. PMID: 15954165.

ERbeta isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates.

Europe PMC ID: 15954165


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References: 10 entries

Zannoni et al. 2016. Histopathology. 68(4):541-8. PMID: 26132417.

Li et al. 2015. Oncol Lett. 10(4):2341-2346. PMID: 26622848.

Sexual dimorphism in medulloblastoma features.

Cytoplasm estrogen receptor β5 as an improved prognostic factor in thymoma and thymic carcinoma progression.

Gender effect in experimental models of human medulloblastoma: does the estrogen receptor β signaling play a role?

Ciucci et al. 2014. PLoS One. 9(7):e101623. PMID: 25000562.

Collins et al. 2009. BMC Cancer. 9:330. PMID: 19758455.

Expression of oestrogen receptors, ERalpha, ERbeta, and ERbeta variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERalpha.

Wong et al. 2005. J Pathol. 207(1):53-60. PMID: 15954165.

ERbeta isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates.


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