Anti-Estrogen Receptor ß1 [PPG5/10]
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- References (16)
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| Catalogue Number | 153631 |
| Applications | IHC IF WB |
| Antigen/Gene or Protein Targets | Estrogen Receptor β1 |
| Synonyms | Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2 |
| Reactivity | Human, Pig, Primate, Rat, Sheep, Rhesus macaque, Cynomolgus monkey, Turtle and Goose |
| Relevance | Estrogen receptors are commonly over-expressed in cancers. Clone PPG5/10 recognizes Estrogen Receptor Beta (ERβ) 1 and is useful in determining the expression of ERβ1 in cancer cells, mainly via immunohistochemistry. |
| Host | Mouse |
| Immunogen | Synthetic peptide CEDSKSKEGSQNPQSQ derived from the C terminus of human ERβ1 |
| Positive Control | Ovary |
| Subclass | IgG2a |
| Molecular Weight (kDa) | 59 |
| Myeloma Used | Sp2/0-Ag14 |
| Strain | Balb/c |
| Notes |
Suggested dilutions for use Western blot 1:500 Immunohistochemistry 1:5 – 1:50 Immunofluorescence 1:250 Research Areas: Endocrinology;Cancer;Fertility;Immunology;Neurobiology |
| Research Area | Cancer, Immunology, Neurobiology |
References: 16 entries
Zannoni et al. 2016. Histopathology. 68(4):541-8. PMID: 26132417.
Sexual dimorphism in medulloblastoma features.
Europe PMC ID: 26132417
Gender effect in experimental models of human medulloblastoma: does the estrogen receptor β signaling play a role?
Europe PMC ID: 25000562
Ciucci et al. 2014. PLoS One. 9(7):e101623. PMID: 25000562.
Asgari et al. 2011. Diagn Pathol. 6:61. PMID: 21733187.
Estrogen receptor beta expression in prostate adenocarcinoma.
Europe PMC ID: 21733187
Collins et al. 2009. BMC Cancer. 9:330. PMID: 19758455.
Expression of oestrogen receptors, ERalpha, ERbeta, and ERbeta variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERalpha.
Europe PMC ID: 19758455
Schiessl et al. 2005. J Histochem Cytochem. 53(12):1441-9. PMID: 15983116.
Wong et al. 2005. J Pathol. 207(1):53-60. PMID: 15954165.
ERbeta isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates.
Europe PMC ID: 15954165
Expression of endothelial NO synthase, inducible NO synthase, and estrogen receptors alpha and beta in placental tissue of normal, preeclamptic, and intrauterine growth-restricted pregnancies.
Europe PMC ID: 15983116
Sierens et al. 2004. J Mol Endocrinol. 32(3):703-18. PMID: 15171710.
Cloning of oestrogen receptor beta from Old and New World primates: identification of splice variants and functional analysis.
Europe PMC ID: 15171710
Torlakovic et al. 2002. Hum Pathol. 33(6):646-51. PMID: 12152165.
Prostate carcinoma expression of estrogen receptor-beta as detected by PPG5/10 antibody has positive association with primary Gleason grade and Gleason score.
Europe PMC ID: 12152165
Add a reference
References: 16 entries
Zannoni et al. 2016. Histopathology. 68(4):541-8. PMID: 26132417.
Sexual dimorphism in medulloblastoma features.
Gender effect in experimental models of human medulloblastoma: does the estrogen receptor β signaling play a role?
Ciucci et al. 2014. PLoS One. 9(7):e101623. PMID: 25000562.
Asgari et al. 2011. Diagn Pathol. 6:61. PMID: 21733187.
Estrogen receptor beta expression in prostate adenocarcinoma.
Collins et al. 2009. BMC Cancer. 9:330. PMID: 19758455.
Expression of oestrogen receptors, ERalpha, ERbeta, and ERbeta variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERalpha.
Schiessl et al. 2005. J Histochem Cytochem. 53(12):1441-9. PMID: 15983116.
Wong et al. 2005. J Pathol. 207(1):53-60. PMID: 15954165.
ERbeta isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates.
Expression of endothelial NO synthase, inducible NO synthase, and estrogen receptors alpha and beta in placental tissue of normal, preeclamptic, and intrauterine growth-restricted pregnancies.
Sierens et al. 2004. J Mol Endocrinol. 32(3):703-18. PMID: 15171710.
Cloning of oestrogen receptor beta from Old and New World primates: identification of splice variants and functional analysis.
Torlakovic et al. 2002. Hum Pathol. 33(6):646-51. PMID: 12152165.
Prostate carcinoma expression of estrogen receptor-beta as detected by PPG5/10 antibody has positive association with primary Gleason grade and Gleason score.
Add a reference