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Anti-Estrogen Receptor ß1 [PPG5/10]

Info

Catalogue Number 153631
Applications IHC IF WB
Antigen/Gene or Protein Targets Estrogen Receptor β1
Synonyms Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2
Reactivity Human, Pig, Primate, Rat, Sheep, Rhesus macaque, Cynomolgus monkey, Turtle and Goose
Relevance Estrogen receptors are commonly over-expressed in cancers. Clone PPG5/10 recognizes Estrogen Receptor Beta (ERβ) 1 and is useful in determining the expression of ERβ1 in cancer cells, mainly via immunohistochemistry.
Host Mouse
Immunogen Synthetic peptide CEDSKSKEGSQNPQSQ derived from the C terminus of human ERβ1
Positive Control Ovary
Subclass IgG2a
Molecular Weight (kDa) 59
Myeloma Used Sp2/0-Ag14
Strain Balb/c
Notes Suggested dilutions for use

Western blot 1:500
Immunohistochemistry 1:5 – 1:50
Immunofluorescence 1:250

Research Areas: Endocrinology;Cancer;Fertility;Immunology;Neurobiology
Research Area Cancer, Immunology, Neurobiology

References

There are 16 reference entries for this reagent.

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References: 16 entries

Zannoni et al. 2016. Histopathology. 68(4):541-8. PMID: 26132417.

Sexual dimorphism in medulloblastoma features.

Europe PMC ID: 26132417

Gender effect in experimental models of human medulloblastoma: does the estrogen receptor β signaling play a role?

Europe PMC ID: 25000562

Ciucci et al. 2014. PLoS One. 9(7):e101623. PMID: 25000562.

Asgari et al. 2011. Diagn Pathol. 6:61. PMID: 21733187.

Estrogen receptor beta expression in prostate adenocarcinoma.

Europe PMC ID: 21733187

Collins et al. 2009. BMC Cancer. 9:330. PMID: 19758455.

Expression of oestrogen receptors, ERalpha, ERbeta, and ERbeta variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERalpha.

Europe PMC ID: 19758455

Schiessl et al. 2005. J Histochem Cytochem. 53(12):1441-9. PMID: 15983116.

Wong et al. 2005. J Pathol. 207(1):53-60. PMID: 15954165.

ERbeta isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates.

Europe PMC ID: 15954165

Expression of endothelial NO synthase, inducible NO synthase, and estrogen receptors alpha and beta in placental tissue of normal, preeclamptic, and intrauterine growth-restricted pregnancies.

Europe PMC ID: 15983116

Sierens et al. 2004. J Mol Endocrinol. 32(3):703-18. PMID: 15171710.

Cloning of oestrogen receptor beta from Old and New World primates: identification of splice variants and functional analysis.

Europe PMC ID: 15171710

Torlakovic et al. 2002. Hum Pathol. 33(6):646-51. PMID: 12152165.

Prostate carcinoma expression of estrogen receptor-beta as detected by PPG5/10 antibody has positive association with primary Gleason grade and Gleason score.

Europe PMC ID: 12152165


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References: 16 entries

Zannoni et al. 2016. Histopathology. 68(4):541-8. PMID: 26132417.

Sexual dimorphism in medulloblastoma features.

Gender effect in experimental models of human medulloblastoma: does the estrogen receptor β signaling play a role?

Ciucci et al. 2014. PLoS One. 9(7):e101623. PMID: 25000562.

Asgari et al. 2011. Diagn Pathol. 6:61. PMID: 21733187.

Estrogen receptor beta expression in prostate adenocarcinoma.

Collins et al. 2009. BMC Cancer. 9:330. PMID: 19758455.

Expression of oestrogen receptors, ERalpha, ERbeta, and ERbeta variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERalpha.

Schiessl et al. 2005. J Histochem Cytochem. 53(12):1441-9. PMID: 15983116.

Wong et al. 2005. J Pathol. 207(1):53-60. PMID: 15954165.

ERbeta isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates.

Expression of endothelial NO synthase, inducible NO synthase, and estrogen receptors alpha and beta in placental tissue of normal, preeclamptic, and intrauterine growth-restricted pregnancies.

Sierens et al. 2004. J Mol Endocrinol. 32(3):703-18. PMID: 15171710.

Cloning of oestrogen receptor beta from Old and New World primates: identification of splice variants and functional analysis.

Torlakovic et al. 2002. Hum Pathol. 33(6):646-51. PMID: 12152165.

Prostate carcinoma expression of estrogen receptor-beta as detected by PPG5/10 antibody has positive association with primary Gleason grade and Gleason score.


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