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Info
Catalogue Number | 153510 |
Applications | ELISA IHC WB |
Antigen/Gene or Protein Targets | CD119 |
Synonyms | Interferon gamma receptor 1, IFN gamma receptor 1 |
Reactivity | Mouse |
Relevance | The monoclonal antibody 11F4 recognizes mouse CD119 also known as IFN gamma receptor 1. CD119 heterodimerizes with IFN gamma receptor 2 (AF-1) forming the Class II cytokine receptor. The ligand IFN gamma binds IFN gamma receptor 1 subunit but signal transduction transpires via the IFN gamma receptor 2 subunit. The receptor is involved in host defense, expression is broad including B cells, NK cells, macrophages and dendritic cells as well as other non-hematopoietic cell types. |
Host | Mouse |
Immunogen | CD119 |
Subclass | IgG1 |
Notes | Purified using protein G |
Research Area | Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology |
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