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Anti-HuD/HuC/HuB [16A11]

Info

Catalogue Number 153503
Applications ELISA IHC IF WB
Antigen/Gene or Protein Targets HuD
Synonyms ELAV-like protein 4
Reactivity Human
Relevance HuD otherwise known as ELAV-like protein 4 is a protein that in humans is encoded by the ELAVL4 gene. The HuD/ELAVL4 protein is an RNA-binding protein.

HuD is expressed only in neurons and it binds to AU-rich element-containing mRNAs. As a result of this interaction the half-life of the transcript is increased. HuD is important in neurons during brain development and plasticity.

The 16A11 anti-HuD monoclonal is now a classic reagent for the identification of neurons.
Host Mouse
Immunogen Peptide
Subclass IgG2b
Research Area Developmental Biology, Gene Expression, Neurobiology

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