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Anti-HuD [15A9] (ChIP Grade)
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Catalogue Number 153502
Applications ChIP ELISA IHC IP WB
Antigen/Gene or Protein Targets HuD
Synonyms ELAV-like protein 4
Reactivity Human
Relevance HuD otherwise known as ELAV-like protein 4 is a protein that in humans is encoded by the ELAVL4 gene. The HuD/ELAVL4 protein is an RNA-binding protein. HuD is expressed only in neurons and it binds to AU-rich element-containing mRNAs. As a result of this interaction the half-life of the transcript is increased. HuD is important in neurons during brain development and plasticity.

Monoclonal 15A9 was generated against a unique HuD peptide and does not react with HuR, HuC, or Hel-N1. Monoclonal 15A9 works well in western blot, IHC and provides an excellent marker for neuronal cells. However, it was specifically selected becasue of its abiity to supershift HuD/mRNA ribonucleoprotein complexes. Thus, it is the ideal reagent for CHIP or RIP studies to specifically identify novel HuD targets in neuronal cells.
Host Mouse
Subclass IgG2b
Research Area Developmental Biology, Gene Expression, Neurobiology

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