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Anti-Cytokeratin 2e [LHK2E]

Invented at Queen Mary University of London

Info

Catalogue Number 153494
Applications IHC WB
Antigen/Gene or Protein Targets Keratin K2e
Synonyms CK 2e antibody, Cytokeratin-2e antibody, Epithelial keratin-2e antibody, K2e antibody, Keratin type II cytoskeletal 2 epidermal antibody, Keratin-2 epidermis antibody, KRT2 antibody, KRT2A antibody, KRT2E antibody, Type-II keratin Kb2 antibody
Reactivity Human
Relevance The cytoskeleton in keratinocytes is a complex of highly homologous structural proteins derived from two families of type I and type II polypeptides. Keratin K2e is a type II polypeptide that is expressed in epidermis late in differentiation. K2e expression in skin is sensitive to keratinocyte activation but its up-regulation in oral lesions is a reflection of the degree of orthokeratinization.
Host Mouse
Immunogen C terminus of the K2e polypeptide (synthetic peptide NH2-GEAFGSSVTFSFR-COOH)
Subclass IgM
Myeloma Used Sp2/0-Ag14
Strain Balb/c
Research Area Cancer, Cell Signaling & Signal Transduction

References

There are 2 reference entries for this reagent.

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References: 2 entries

Bloor et al. 2003. Am J Pathol. 162(3):963-75. PMID: 12598329.

IHC

Expression of keratin K2e in cutaneous and oral lesions: association with keratinocyte activation, proliferation, and keratinization.

Europe PMC ID: 12598329


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References: 2 entries

Bloor et al. 2003. Am J Pathol. 162(3):963-75. PMID: 12598329.

IHC

Expression of keratin K2e in cutaneous and oral lesions: association with keratinocyte activation, proliferation, and keratinization.


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Inventor Information

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