Anti-Cytokeratin 2e [LHK2E]
Invented at Queen Mary University of London
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 153494 |
| Applications | IHC WB |
| Antigen/Gene or Protein Targets | Keratin K2e |
| Synonyms | CK 2e antibody, Cytokeratin-2e antibody, Epithelial keratin-2e antibody, K2e antibody, Keratin type II cytoskeletal 2 epidermal antibody, Keratin-2 epidermis antibody, KRT2 antibody, KRT2A antibody, KRT2E antibody, Type-II keratin Kb2 antibody |
| Reactivity | Human |
| Relevance | The cytoskeleton in keratinocytes is a complex of highly homologous structural proteins derived from two families of type I and type II polypeptides. Keratin K2e is a type II polypeptide that is expressed in epidermis late in differentiation. K2e expression in skin is sensitive to keratinocyte activation but its up-regulation in oral lesions is a reflection of the degree of orthokeratinization. |
| Host | Mouse |
| Immunogen | C terminus of the K2e polypeptide (synthetic peptide NH2-GEAFGSSVTFSFR-COOH) |
| Subclass | IgM |
| Myeloma Used | Sp2/0-Ag14 |
| Strain | Balb/c |
| Research Area | Cancer, Cell Signaling & Signal Transduction |
References: 2 entries
Bloor et al. 2003. Am J Pathol. 162(3):963-75. PMID: 12598329.
IHC
Expression of keratin K2e in cutaneous and oral lesions: association with keratinocyte activation, proliferation, and keratinization.
Europe PMC ID: 12598329
Add a reference
References: 2 entries
Bloor et al. 2003. Am J Pathol. 162(3):963-75. PMID: 12598329.
IHC
Expression of keratin K2e in cutaneous and oral lesions: association with keratinocyte activation, proliferation, and keratinization.
Add a reference
