Anti-C-kit (CD117) [2C11]
Invented at A*STAR Accelerate Technologies Pte Ltd
- Datasheet
- References (2)
- Inventor Info
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| Catalogue Number | 153479 |
| Applications | FACS WB |
| Antigen/Gene or Protein Targets | C-kit |
| Synonyms | C Kit antibody, c-Kit antibody, CD117 antibody |
| Reactivity | Human |
| Relevance | C-kit, also known as CD117, is expressed on the surface of hematopoietic stem cells. C-kit is a receptor tyrosine kinase that is overexpressed in > 70% of gastrointestinal stromal tumors (GISTs). |
| Host | Mouse |
| Immunogen | GST-fusion protein containing 315-519 residues of human c-kit. c-kit. This region is in the extracellular domain of c-kit. |
| Subclass | IgG1 |
| Myeloma Used | Sp2/0-Ag14 |
| Strain | Balb/c |
| Research Area | Cancer, Immunology |
References: 2 entries
Bellone et al. 2001. Cancer Res. 61(5):2200-6. PMID: 11280787.
Aberrant activation of c-kit protects colon carcinoma cells against apoptosis and enhances their invasive potential.
Europe PMC ID: 11280787
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References: 2 entries
Bellone et al. 2001. Cancer Res. 61(5):2200-6. PMID: 11280787.
Aberrant activation of c-kit protects colon carcinoma cells against apoptosis and enhances their invasive potential.
Add a reference
