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Anti-C-kit (CD117) [2C11]

Invented at A*STAR Accelerate Technologies Pte Ltd

Info

Catalogue Number 153479
Applications FACS WB
Antigen/Gene or Protein Targets C-kit
Synonyms C Kit antibody, c-Kit antibody, CD117 antibody
Reactivity Human
Relevance C-kit, also known as CD117, is expressed on the surface of hematopoietic stem cells. C-kit is a receptor tyrosine kinase that is overexpressed in > 70% of gastrointestinal stromal tumors (GISTs).
Host Mouse
Immunogen GST-fusion protein containing 315-519 residues of human c-kit. c-kit. This region is in the extracellular domain of c-kit.
Subclass IgG1
Myeloma Used Sp2/0-Ag14
Strain Balb/c
Research Area Cancer, Immunology

References

There are 2 reference entries for this reagent.

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References: 2 entries

Bellone et al. 2001. Cancer Res. 61(5):2200-6. PMID: 11280787.

Aberrant activation of c-kit protects colon carcinoma cells against apoptosis and enhances their invasive potential.

Europe PMC ID: 11280787


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References: 2 entries

Bellone et al. 2001. Cancer Res. 61(5):2200-6. PMID: 11280787.

Aberrant activation of c-kit protects colon carcinoma cells against apoptosis and enhances their invasive potential.


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Inventor Information

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