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Anti-ACE (somatic isoform-2) [L10P4F3*F9]

Invented by Ayham Alnabulsi at Vertebrate Antibodies Limited

Info

Catalogue Number 153472
Applications ELISA IHC
Antigen/Gene or Protein Targets Angiotensin Converting Enzyme, Somatic Isoform-2, (P12821-2)
Synonyms ACE antibody
ACE T antibody
ACE_HUMAN antibody
ACE1 antibody
Angiotensin converting enzyme somatic isoform antibody
Angiotensin converting enzyme testis specific isoform antibody
Angiotensin-converting enzyme antibody
Reactivity Human
Relevance Ace is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic forms and the testicular form, respectively, that are equally active. This antibody is specific to ACE-somatic isoform 2 (P12821-2).
Host Mouse
Immunogen Ovalbumin-conjugated synthetic peptide QFHPFSQHT (C-terminal sequence)
Positive Control IHC - formalin-fixed, paraffin-embedded hepatocellular carcinoma sections
Subclass IgG
Myeloma Used P3X63Ag8.653
Strain Balb/c
Notes Recommended Usage Conditions: IHC - neat (antigen retrieval: microwave 20 min @ 800W in 10 mM citrate buffer, pH 6.0)
Research Area Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism

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