Anti-ACE (somatic isoform-2) [L10P4F3*F9]
Invented by Ayham Alnabulsi from Vertebrate Antibodies Limited
Invented at Vertebrate Antibodies Limited
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Info
| Catalogue Number | 153472 |
| Applications | ELISA IHC |
| Antigen/Gene or Protein Targets | Angiotensin Converting Enzyme, Somatic Isoform-2, (P12821-2) |
| Synonyms |
ACE antibody ACE T antibody ACE_HUMAN antibody ACE1 antibody Angiotensin converting enzyme somatic isoform antibody Angiotensin converting enzyme testis specific isoform antibody Angiotensin-converting enzyme antibody |
| Reactivity | Human |
| Relevance | Ace is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic forms and the testicular form, respectively, that are equally active. This antibody is specific to ACE-somatic isoform 2 (P12821-2). |
| Host | Mouse |
| Immunogen | Ovalbumin-conjugated synthetic peptide QFHPFSQHT (C-terminal sequence) |
| Positive Control | IHC - formalin-fixed, paraffin-embedded hepatocellular carcinoma sections |
| Subclass | IgG |
| Myeloma Used | P3X63Ag8.653 |
| Strain | Balb/c |
| Notes | Recommended Usage Conditions: IHC - neat (antigen retrieval: microwave 20 min @ 800W in 10 mM citrate buffer, pH 6.0) |
| Research Area | Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism |
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