Poly(HPhMA- co -HEMA) Small Molecule (Tool Compound)
Invented by Prof Chris Denning from University of Nottingham , Prof Morgan Alexander from University of Nottingham , Dr Adam Celiz from University of Nottingham , Dr Asha Patel from University of Nottingham
Invented at University of Nottingham
- Datasheet
- References (4)
- Inventor Info
Info
| Antigen/Gene or Protein Targets | Synthetic polymer substrate to support Human Pluripotent Stem Cell Expansion |
| Synonyms | hPSCs, hESCs, N -(4-hydroxyphenyl)meth-acrylamide, polyHEMA |
| Relevance | Preliminary findings show that blockade of integrin β1 and αV β5 significantly reduces hPSC adhesion to poly(HPhMA-co-HEMA) in StemPro media. |
| Molecular Formula | (C10H11NO2)n(C6H10O3)m |
| In vitro applications | Expansion and multilineage differentiation of human pluripotent stem cells |
| Solubility | 5 % Ethanol |
| Research Area | Cancer, Drug Discovery & Development, Stem Cell Biology |
| Storage | Ambient |
References: 4 entries
Celiz et al. 2015. Adv Mater. 27(27):4006-12. PMID: 26033422.
Discovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multilineage Differentiation.
Europe PMC ID: 26033422
Celiz et al. 2014. Nat Mater. 13(6):570-9. PMID: 24845996.
Materials for stem cell factories of the future.
Europe PMC ID: 24845996
Add a reference
References: 4 entries
Celiz et al. 2015. Adv Mater. 27(27):4006-12. PMID: 26033422.
Discovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multilineage Differentiation.
Celiz et al. 2014. Nat Mater. 13(6):570-9. PMID: 24845996.
Materials for stem cell factories of the future.
Add a reference
