Cancer Research Technology
Log in Register
Menu

Anti-VHL [LIZ167C]

Info

Catalogue Number 153442
Antigen/Gene or Protein Targets VHL
Synonyms von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
Relevance VHL is Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. It seems to act as target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions. It is involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases.
Research Area Cancer, Cell Cycle, Epigenetics & Nuclear Signalling, Metabolism

References

There are 0 reference entries for this reagent.

References: 0 entry

There is no reference for this reagent yet, feel free to use the button below to suggest one.

Add a reference

References: 0 entry

There is no reference for this reagent yet, feel free to use the button below to suggest one.

Add a reference

Inventor Information

No inventors are currently linked to this reagent.

Add an inventor