Anti-Keratin 10 [LHP1]
Invented by Prof Irene Leigh from Queen Mary University of London
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 153430 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | Keratin 10 |
| Synonyms |
CK 10 antibody, CK-10 antibody, Cytokeratin-10 antibody, EHK antibody, K10 antibody, K1C10_HUMAN antibody, Keratin 10 antibody, Keratin 10 type I antibody, Keratin antibody, Keratin type i cytoskeletal 10 antibody, Keratin type I cytoskeletal 59 kDa antibody, Keratin-10 antibody, Keratin10 antibody, KPP antibody, KRT10 antibody, type I cytoskeletal 10 antibody |
| Reactivity | Human |
| Relevance | Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 1 and 10 are differentiation-specific keratins that are the predominant keratins in suprabasal keratinocytes in stratified epthelia. Keratin 10 is a suprabasal marker of differentiation in stratified squamous epithelia. Mutations in keratins 1 and 10 cause epidermolytic hyperkeratosis. |
| Host | Mouse |
| Immunogen | Epidermis from Psoriasis patient (crude extract) |
| Subclass | IgG1 |
| Myeloma Used | Sp2/0-Ag14 |
| Strain | Balb/c |
| Research Area | Cancer, Cell Type or Organelle Marker |
References: 2 entries
Lane et al. 1985. Ann N Y Acad Sci. 455:241-58. PMID: 2417515.
Keratin antigens in differentiating skin.
Europe PMC ID: 2417515
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References: 2 entries
Lane et al. 1985. Ann N Y Acad Sci. 455:241-58. PMID: 2417515.
Keratin antigens in differentiating skin.
Add a reference
