Cancer Research Technology
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Catalogue Number 153430
Applications ELISA IHC WB
Antigen/Gene or Protein Targets Keratin 10
Synonyms CK 10 antibody, CK-10 antibody, Cytokeratin-10 antibody, EHK antibody, K10 antibody, K1C10_HUMAN antibody, Keratin 10 antibody, Keratin 10 type I antibody, Keratin antibody, Keratin type i cytoskeletal 10 antibody, Keratin type I cytoskeletal 59 kDa antibody,
Keratin-10 antibody, Keratin10 antibody, KPP antibody, KRT10 antibody, type I cytoskeletal 10 antibody
Reactivity Human
Relevance Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue- and differentiation-specific expression profiles. Keratins 1 and 10 are differentiation-specific keratins that are the predominant keratins in suprabasal keratinocytes in stratified epthelia. Keratin 10 is a suprabasal marker of differentiation in stratified squamous epithelia. Mutations in keratins 1 and 10 cause epidermolytic hyperkeratosis.
Host Mouse
Immunogen Epidermis from Psoriasis patient (crude extract)
Subclass IgG1
Myeloma Used Sp2/0-Ag14
Strain Balb/c
Research Area Cancer, Cell Type or Organelle Marker

References

There are 2 reference entries for this reagent.

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References: 2 entries

Lane et al. 1985. Ann N Y Acad Sci. 455:241-58. PMID: 2417515.

Keratin antigens in differentiating skin.

Europe PMC ID: 2417515


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References: 2 entries

Lane et al. 1985. Ann N Y Acad Sci. 455:241-58. PMID: 2417515.

Keratin antigens in differentiating skin.


Add a reference