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Anti-Ribophorin-1 [CEL5C]

Invented by Prof Birgit Lane at A*STAR Accelerate Technologies Pte Ltd

Info

Catalogue Number 153410
Applications IP WB
Antigen/Gene or Protein Targets ribophorin type 1
Synonyms OST1; RBPH1
Reactivity Xenopus laevis
Relevance Ribophorin I is an essential subunit of oligosaccharyltransferase (OST), which is also known as dolichyl-diphosphooligosaccharide--protein glycosyltransferase. OST catalyses the transfer of an oligosaccharide from dolichol pyrophosphate to selected asparagine residues of nascent polypeptides as they are translocated into the lumen of the rough endoplasmic reticulum. Ribophorin I and OST48 are thought to be responsible for OST catalytic activity. Both yeast and mammalian proteins are glycosylated but the sites are not conserved. Glycosylation may contribute towards general solubility but is unlikely to be involved in a specific biochemical function. Most family members are predicted to have a transmembrane helix at the C terminus of this region.
Host Mouse
Immunogen Nuclei formed in vitro in Xenopus egg extract
Subclass IgG1
Molecular Weight (kDa) 65
Research Area Cell Signaling & Signal Transduction

References

There are 2 reference entries for this reagent.

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References: 2 entries

Addinall et al. 2001. J Biol Chem. 276(19):15939-44. PMID: 11278950.

Phosphorylation by cdc2-CyclinB1 kinase releases cytoplasmic dynein from membranes.

Europe PMC ID: 11278950


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References: 2 entries

Addinall et al. 2001. J Biol Chem. 276(19):15939-44. PMID: 11278950.

Phosphorylation by cdc2-CyclinB1 kinase releases cytoplasmic dynein from membranes.


Add a reference

Inventor Information