Anti-Myb [10A3]
Invented at University of Cambridge
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 153401 |
| Applications | IP WB |
| Antigen/Gene or Protein Targets | Xenopus MYB / c-Myb |
| Synonyms | MYB; C-myb_CDS; C-myb8B_CDS; C-myb protein (140 AA); C-myb10A_CDS; C-myb13A_CDS; Efg; Transcriptional activator Myb; C-myb; C-myb14A_CDS; Cmyb; Proto-oncogene c-Myb |
| Reactivity | Human, Mouse, Xenopus laevis and Zebrafish |
| Relevance | MYB / c-Myb is a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants. |
| Host | Mouse |
| Immunogen | Recombinant v-myb protein |
| Subclass | IgG2a |
| Molecular Weight (kDa) | 55 |
| Notes | This antibody does not react with human Hsp60 nor with E. coli GroEL proteins. |
| Research Area | Cancer |
References: 2 entries
Benes et al. 2007. Leuk Res. 31(10):1421-31. PMID: 17624428.
Retinoic acid enhances differentiation of v-myb-transformed monoblasts induced by okadaic acid.
Europe PMC ID: 17624428
Add a reference
References: 2 entries
Benes et al. 2007. Leuk Res. 31(10):1421-31. PMID: 17624428.
Retinoic acid enhances differentiation of v-myb-transformed monoblasts induced by okadaic acid.
Add a reference
