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Anti-MUC2 [996/1]

Info

Catalogue Number 153398
Applications FACS IHC WB
Antigen/Gene or Protein Targets MUC2
Synonyms MUC-2; SMUC; MLP , Mucin2
Reactivity Human
Relevance Mucin 2/MUC2 is a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight.
Host Mouse
Immunogen MUC-2 tandem repeat peptide
Positive Control Normal colon
Subclass IgG1
Molecular Weight (kDa) 540
Myeloma Used NS0
Research Area Cancer, Cell Cycle, Epigenetics & Nuclear Signalling

References

There are 18 reference entries for this reagent.

View All References

References: 18 entries

Wang et al. 2015. JPEN J Parenter Enteral Nutr. 39(6):688-97. PMID: 24836948.

Forbester et al. 2015. Infect Immun. 83(7):2926-34. PMID: 25964470.

Interaction of Salmonella enterica Serovar Typhimurium with Intestinal Organoids Derived from Human Induced Pluripotent Stem Cells.

Europe PMC ID: 25964470

Glutamine Improves Innate Immunity and Prevents Bacterial Enteroinvasion During Parenteral Nutrition.

Europe PMC ID: 24836948

Luo et al. 2014. Infect Immun. 82(2):509-21. PMID: 24478067.

He et al. 2013. PLoS One. 8(12):e79769. PMID: 24324582.

High MUC2 expression in ovarian cancer is inversely associated with the M1/M2 ratio of tumor-associated macrophages and patient survival time.

Europe PMC ID: 24324582

Enterotoxigenic Escherichia coli secretes a highly conserved mucin-degrading metalloprotease to effectively engage intestinal epithelial cells.

Europe PMC ID: 24478067

Pierre et al. 2013. JPEN J Parenter Enteral Nutr. 37(3):401-9. PMID: 23064255.

Cranberry proanthocyanidins improve the gut mucous layer morphology and function in mice receiving elemental enteral nutrition.

Europe PMC ID: 23064255

Algamas-Dimantov et al. 2012. J Lipid Res. 53(6):1056-70. PMID: 22357704.

Amelioration of diabesity-induced colorectal ontogenesis by omega-3 fatty acids in mice.

Europe PMC ID: 22357704

Vermeulen et al. 2010. Nat Cell Biol. 12(5):468-76. PMID: 20418870.

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment.

Europe PMC ID: 20418870

Guilmeau et al. 2010. Oncogene. 29(7):992-1002. PMID: 19935714.

Heterogeneity of Jagged1 expression in human and mouse intestinal tumors: implications for targeting Notch signaling.

Europe PMC ID: 19935714

Durrant et al. 1994. Eur J Cancer. 30A(3):355-63. PMID: 8204359.

Production of monoclonal antibodies recognising the peptide core of MUC2 intestinal mucin.

Europe PMC ID: 8204359


Add a reference

References: 18 entries

Wang et al. 2015. JPEN J Parenter Enteral Nutr. 39(6):688-97. PMID: 24836948.

Forbester et al. 2015. Infect Immun. 83(7):2926-34. PMID: 25964470.

Interaction of Salmonella enterica Serovar Typhimurium with Intestinal Organoids Derived from Human Induced Pluripotent Stem Cells.

Glutamine Improves Innate Immunity and Prevents Bacterial Enteroinvasion During Parenteral Nutrition.

Luo et al. 2014. Infect Immun. 82(2):509-21. PMID: 24478067.

He et al. 2013. PLoS One. 8(12):e79769. PMID: 24324582.

High MUC2 expression in ovarian cancer is inversely associated with the M1/M2 ratio of tumor-associated macrophages and patient survival time.

Enterotoxigenic Escherichia coli secretes a highly conserved mucin-degrading metalloprotease to effectively engage intestinal epithelial cells.

Pierre et al. 2013. JPEN J Parenter Enteral Nutr. 37(3):401-9. PMID: 23064255.

Cranberry proanthocyanidins improve the gut mucous layer morphology and function in mice receiving elemental enteral nutrition.

Algamas-Dimantov et al. 2012. J Lipid Res. 53(6):1056-70. PMID: 22357704.

Amelioration of diabesity-induced colorectal ontogenesis by omega-3 fatty acids in mice.

Vermeulen et al. 2010. Nat Cell Biol. 12(5):468-76. PMID: 20418870.

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment.

Guilmeau et al. 2010. Oncogene. 29(7):992-1002. PMID: 19935714.

Heterogeneity of Jagged1 expression in human and mouse intestinal tumors: implications for targeting Notch signaling.

Durrant et al. 1994. Eur J Cancer. 30A(3):355-63. PMID: 8204359.

Production of monoclonal antibodies recognising the peptide core of MUC2 intestinal mucin.


Add a reference

Inventor Information

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