Anti-cMyc [JAC6]
Invented at The Institute of Cancer Research
- Datasheet
- References (14)
- Inventor Info
Info
| Catalogue Number | 153385 |
| Applications | IHC IF IP WB |
| Antigen/Gene or Protein Targets | myc |
| Synonyms | Myc proto oncogene protein; c Myc |
| Reactivity | Human |
| Relevance | Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes. |
| Host | Rat |
| Immunogen | Synthetic peptide, corresponding to amino acids 408-439 of Human c-Myc |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 53 |
| Research Area | Apoptosis and Programmed Cell Death, Cancer, Cell Cycle, Immunology |
References: 14 entries
Su et al. 2015. J Cell Sci. 128(22):4063-73. PMID: 26430213.
Regulation of polycystin-1 ciliary trafficking by motifs at its C-terminus and polycystin-2 but not by cleavage at the GPS site.
Europe PMC ID: 26430213
von Philipsborn et al. 2014. Curr Biol. 24(3):242-51. PMID: 24440391.
Cellular and behavioral functions of fruitless isoforms in Drosophila courtship.
Europe PMC ID: 24440391
Coleman et al. 2011. J Biol Chem. 286(19):17205-16. PMID: 21454556.
Critical role of the beta-subunit CDC50A in the stable expression, assembly, subcellular localization, and lipid transport activity of the P4-ATPase ATP8A2.
Europe PMC ID: 21454556
Ringli et al. 2010. Plant J. 63(4):662-9. PMID: 20545889.
The hydroxyproline-rich glycoprotein domain of the Arabidopsis LRX1 requires Tyr for function but not for insolubilization in the cell wall.
Europe PMC ID: 20545889
Paternal effect of the nuclear formin-like protein MISFIT on Plasmodium development in the mosquito vector.
Europe PMC ID: 19662167
Bushell et al. 2009. PLoS Pathog. 5(8):e1000539. PMID: 19662167.
Fernando et al. 2008. Clin Cancer Res. 14(5):1529-39. PMID: 18316578.
Tumor escape from endogenous, extracellular matrix-associated angiogenesis inhibitors by up-regulation of multiple proangiogenic factors.
Europe PMC ID: 18316578
Zavortink et al. 2005. J Cell Sci. 118(Pt 22):5381-92. PMID: 16280552.
Tum/RacGAP50C provides a critical link between anaphase microtubules and the assembly of the contractile ring in Drosophila melanogaster.
Europe PMC ID: 16280552
Add a reference
References: 14 entries
Su et al. 2015. J Cell Sci. 128(22):4063-73. PMID: 26430213.
Regulation of polycystin-1 ciliary trafficking by motifs at its C-terminus and polycystin-2 but not by cleavage at the GPS site.
von Philipsborn et al. 2014. Curr Biol. 24(3):242-51. PMID: 24440391.
Cellular and behavioral functions of fruitless isoforms in Drosophila courtship.
Coleman et al. 2011. J Biol Chem. 286(19):17205-16. PMID: 21454556.
Critical role of the beta-subunit CDC50A in the stable expression, assembly, subcellular localization, and lipid transport activity of the P4-ATPase ATP8A2.
Ringli et al. 2010. Plant J. 63(4):662-9. PMID: 20545889.
The hydroxyproline-rich glycoprotein domain of the Arabidopsis LRX1 requires Tyr for function but not for insolubilization in the cell wall.
Paternal effect of the nuclear formin-like protein MISFIT on Plasmodium development in the mosquito vector.
Bushell et al. 2009. PLoS Pathog. 5(8):e1000539. PMID: 19662167.
Fernando et al. 2008. Clin Cancer Res. 14(5):1529-39. PMID: 18316578.
Tumor escape from endogenous, extracellular matrix-associated angiogenesis inhibitors by up-regulation of multiple proangiogenic factors.
Zavortink et al. 2005. J Cell Sci. 118(Pt 22):5381-92. PMID: 16280552.
Tum/RacGAP50C provides a critical link between anaphase microtubules and the assembly of the contractile ring in Drosophila melanogaster.
Add a reference
