Anti-CEA/NCA [198]
Invented by Prof Lindy Durrant from University of Nottingham
Invented at University of Nottingham
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 153384 |
| Applications | FACS IHC |
| Antigen/Gene or Protein Targets | CEA/NCA |
| Synonyms | CEACAM5; CEA |
| Reactivity | Human |
| Relevance | Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins, found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. Belongs to the immunoglobulin superfamily, CEA family- contains 7 Ig-like (immunoglobulin-like) domains. |
| Host | Mouse |
| Immunogen | CEA preparation purified from colon carcinoma metastases. Tumor subcellular membranes or viable cells from CEA-producing colon carcinoma cell lines |
| Subclass | IgG1 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Research Area | Cancer, Cell Signaling & Signal Transduction |
References: 4 entries
Reiterer et al. 2007. Cancer Res. 67(16):7765-72. PMID: 17699781.
Platelet-derived growth factor receptor regulates myeloid and monocytic differentiation of HL-60 cells.
Europe PMC ID: 17699781
Byers et al. 1988. J Immunol. 140(11):4050-5. PMID: 2453564.
Potentiation of anti-carcinoembryonic antigen immunotoxin cytotoxicity by monoclonal antibodies reacting with co-expressed carcinoembryonic antigen epitopes.
Europe PMC ID: 2453564
Add a reference
References: 4 entries
Reiterer et al. 2007. Cancer Res. 67(16):7765-72. PMID: 17699781.
Platelet-derived growth factor receptor regulates myeloid and monocytic differentiation of HL-60 cells.
Byers et al. 1988. J Immunol. 140(11):4050-5. PMID: 2453564.
Potentiation of anti-carcinoembryonic antigen immunotoxin cytotoxicity by monoclonal antibodies reacting with co-expressed carcinoembryonic antigen epitopes.
Add a reference
