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Anti-CEA/NCA [198]

Invented by Prof Lindy Durrant at University of Nottingham

Info

Catalogue Number 153384
Applications FACS IHC
Antigen/Gene or Protein Targets CEA/NCA
Synonyms CEACAM5; CEA
Reactivity Human
Relevance Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins, found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. Belongs to the immunoglobulin superfamily, CEA family- contains 7 Ig-like (immunoglobulin-like) domains.
Host Mouse
Immunogen CEA preparation purified from colon carcinoma metastases. Tumor subcellular membranes or viable cells from CEA-producing colon carcinoma cell lines
Subclass IgG1
Myeloma Used P3/NS1/1-Ag4.1
Research Area Cancer, Cell Signaling & Signal Transduction

References

There are 4 reference entries for this reagent.

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References: 4 entries

Reiterer et al. 2007. Cancer Res. 67(16):7765-72. PMID: 17699781.

Platelet-derived growth factor receptor regulates myeloid and monocytic differentiation of HL-60 cells.

Europe PMC ID: 17699781

Byers et al. 1988. J Immunol. 140(11):4050-5. PMID: 2453564.

Potentiation of anti-carcinoembryonic antigen immunotoxin cytotoxicity by monoclonal antibodies reacting with co-expressed carcinoembryonic antigen epitopes.

Europe PMC ID: 2453564


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References: 4 entries

Reiterer et al. 2007. Cancer Res. 67(16):7765-72. PMID: 17699781.

Platelet-derived growth factor receptor regulates myeloid and monocytic differentiation of HL-60 cells.

Byers et al. 1988. J Immunol. 140(11):4050-5. PMID: 2453564.

Potentiation of anti-carcinoembryonic antigen immunotoxin cytotoxicity by monoclonal antibodies reacting with co-expressed carcinoembryonic antigen epitopes.


Add a reference