Anti-CEACAM1 (CD66a) [F7] monoclonal antibody
Invented by Dr Bernhard B. Singer from LeukoCom
Invented at LeukoCom
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Info
![Image thumbnail for Anti-CEACAM1 (CD66a) [F7] monoclonal antibody](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/748b18ed-4ce9-4e38-bee7-d27c0856a3ac.jpg)
| Catalogue Number | 153379 |
| Applications | ELISA FACS IHC IP WB |
| Antigen/Gene or Protein Targets | CEACAM1 |
| Synonyms | CD66, BGP 1, BGP, CD66a, Carcinoembryonic Antigen Related Cell Adhesion Molecule 1; CD66a Antigen; BGP1; BGP; Biliary Glycoprotein 1; Antigen CD66 |
| Reactivity | Rat |
| Relevance | Carcinoembryonic antigen related cell adhesion molecules (CEACAM) (CD66a) belong to the immunoglobulin superfamily. They are highly glycosylated proteins with the typical N-terminal variable Ig-like domain followed by 0-6 constant Ig-like domains. A hydrophobic transmembrane domain with a cytoplasmic tail anchors CEACAM1 to the cell membrane. CEACAM1 is known as an epithelial tumour suppressor and an angiogenic growth factor. |
| Host | Mouse |
| Positive Control | lysate from rat bladder cell line endogenously expressing ratCEACAM1 |
| Subclass | IgG1 kappa |
| Notes |
Does not cross-react with human CEACAM-1, -3. -4, -5, -6, 7 and -8, mouse CEACAM1 and mouse CEACAM2. Binds specific to the N-domain of rat CEACAM1 |
| Research Area | Adhesion, Cancer, Cell Type or Organelle Marker |
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