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Anti-CD29, Recombinant [12G10]

Info

Catalogue Number 153365
Applications ELISA FACS IHC IF IP WB
Antigen/Gene or Protein Targets CD29 (Integrin b1 chain)
Synonyms Integrin Subunit Beta 1; Glycoprotein Iia; MSK12; GPIIA; FNRB; MDF2; Very Late Activation Protein; Beta Polypeptide; Fibronectin Receptor Subunit Beta; Integrin VLA-4 Beta Subunit; CD29 Antigen; VLA-BETA; CD29; VLAB
Reactivity Human
Relevance CD29 is a member of the family of integrins, membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells.
Host Mouse
Immunogen Purified human β1 integrin preparation from HT1080 fibrosarcoma cell extract.
Subclass IgG1
Formulation PBS
Concentration 1mg/ml
Research Area Adhesion, Cancer, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling, Gene Expression, Immunology
Notes 12G10 has been shown to recognize a ligand-induced binding site of human β1 integrin. The binding is increased in the presence of a
fibronectin ligand. This antibody also enhances alpha 5 – beta 1 fibronectin interactions.
Recombinant monoclonal antibody produced from the original monoclonal. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma.

References

There are 1 reference entries for this reagent.

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References: 1 entry

Original hybridoma first published in: Mould et al. 1995. FEBS Lett. 363(1-2):118-22. PMID: 7537221.


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References: 1 entry

Original hybridoma first published in: Mould et al. 1995. FEBS Lett. 363(1-2):118-22. PMID: 7537221.


Add a reference

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