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Anti-Factor VIII:c light chain, Recombinant [RFF-VIII:c/5]

Invented at University College London, Absolute Antibody

Info

Catalogue Number 153359
Applications IF WB
Antigen/Gene or Protein Targets Factor VIII:c light chain
Reactivity Human
Relevance The commonest severe congenital bleeding disorder in all races is haemophilia A. The characteristic defect is a lack of coagulation factor VIII:C. Factor VIII:C is a glycoprotein that functions as a cofactor for factor IXa which, in the presence of calcium and phospholipids, converts factor X to the activated form Xa. This antibody may be used for the purification of Factor VIII from normal plasma and cryoprecipitate.
Host Mouse
Immunogen Purified Human FVIII
Subclass IgG1 kappa
Formulation PBS
Concentration 1mg/ml
Research Area Cardiovascular
Notes Recombinant monoclonal antibody produced from the original monoclonal. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma.

References

There are 1 reference entries for this reagent.

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References: 1 entry

Original hybridoma first published in: Rotblat et al. 1983. J Lab Clin Med. 101(5):736-46. PMID: 6403638.


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References: 1 entry

Original hybridoma first published in: Rotblat et al. 1983. J Lab Clin Med. 101(5):736-46. PMID: 6403638.


Add a reference

Inventor Information